622347-45-9

Upstream product

• 622347-34-6 (4S)-4-benzyl-3-[3-(2,6-dimethoxy-3-methoxymethoxy-5-nitro-phenyl)-(2R)-2-methylpropionyl]-oxazolidin-2-one 
• 622347-43-7 4-(2,6-dimethoxy-3-methoxymethoxy-5-nitro-phenyl)-(3R)-3-methylbutyronitrile 
• 622347-44-8 4-(2,6-dimethoxy-3-methoxymethoxy-5-nitro-phenyl)-(3R)-3-methylbutyraldehyde 
• 622347-36-8 3-(2,6-dimethoxy-3-methoxymethoxy-5-nitro-phenyl)-(2R)-2-methylpropan-1-ol 
• 622347-35-7 3-bromomethyl-2,4-dimethoxy-1-methoxymethoxy-5-nitrobenzene 
• 622347-42-6 (2,6-dimethoxy-3-methoxymethoxy-5-nitro)benzyl alcohol 
• 622347-33-5 2,6-dimethoxy-3-methoxymethoxy-5-nitro-benzaldehyde 
• 622347-41-5 2,6-dimethoxy-3-methoxymethoxy-benzaldehyde 
• 613-45-6 2,4-Dimethoxybenzaldehyde 
• 104202-36-0 1,3-dimethoxy-4-methoxymethoxybenzene 
• 13330-65-9 2,4-dimethoxyphenol 

Downstream Products

• 622347-39-1 2-methyl-but-(2E)-2-enoic acid [(5-hydroxy-3-(4R)-4-hydroxy-(2R)-2-methylheptyl)-2,4-dimethoxy-5-methoxymethoxy-phenyl]amide 
• 622347-38-0 (2E)-2-methyl-but-2-enoic acid {3-[(4R)-4-(tert-butyl-dimethyl-silanyloxy)-(2R)-2-methylheptyl]-2,4-dimethoxy-5-methoxymethoxy-phenyl}amide 
• 622347-46-0 3-[(4R)-4-(tert-butyl-dimethyl-silanyloxy)-(2R)-2-methylheptyl]-2,4-dimethoxy-5-methoxymethoxy-phenylamine 

Relevant academic research and scientific papers

Selective Synthesis of the para-Quinone Region of Geldanamycin

(Matrix presented) The quinone portion of the ansamycin geldanamycin was made with complete selectivity from the 1,4-dihydroquinone generated from a 1,4-bis-methoxymethyl (MOM) ether intermediate. Palladium catalysis with air gave the desired product in 9