622347-56-2

Upstream product

• 824-46-4 methoxyhydroquinone 
• 622347-51-7 (4S)-4-benzyl-3-[3-(2-methoxy-3,6-bis(methoxymethoxy)-5-nitro-phenyl)-(2R)-2-methylpropionyl]-oxazolidin-2-one 
• 622347-53-9 4-(2-methoxy-3,6-bis(methoxymethoxy)-5-nitro-phenyl)-(3R)-3-methylbutyronitrile 
• 622347-54-0 4-(2-methoxy-3,6-bis(methoxymethoxy)-5-nitro-phenyl)-(3R)-3-methylbutyraldehyde 
• 622347-52-8 3-(2-dimethoxy-3,6-methoxymethoxy-5-nitro-phenyl)-(2R)-2-methylpropan-1-ol 
• 622347-50-6 3-bromomethyl-2-methoxy-1,4-bis(methoxymethoxy)-5-nitrobenzene 
• 622347-49-3 (2-methoxy-3,6-bis(methoxymethoxy)-5-nitrophenyl)methanol 
• 622347-48-2 2-methoxy-3,6-bis(methoxymethoxy)-5-nitrobenzaldehyde 
• 622347-47-1 3-hydroxy-2-methoxy-6-methoxymethyl-5-nitrobenzaldehyde 
• 622347-32-4 2-methoxy-3,6-bis(methoxymethoxy)benzaldehyde 
• 131223-60-4 2-methoxy-1,4-bis-methoxymethoxy-benzene 

Downstream Products

• 622347-58-4 2-methyl-but-(2E)-2-enoic acid {3-[(4R)-4-(tert-butyl-dimethyl-silanyloxy)-(2R)-2-methylheptyl]-4-methoxy-2,5-bis(methoxymethoxy)phenyl}amide 
• 622347-59-5 2-methyl-but-(2E)-2-enoic acid [(2,5-dihydroxy-3-(4R)-4-hydroxy-(2R)-2-methylheptyl)-4-methoxy-phenyl]amide 
• 622347-57-3 3-[(4R)-4-(tert-butyl-dimethyl-silanyloxy)-(2R)-2-methyl-heptyl]-4-methoxy-2,5-bis(methoxymethoxy)-phenylamine 

Relevant academic research and scientific papers

Selective Synthesis of the para-Quinone Region of Geldanamycin

(Matrix presented) The quinone portion of the ansamycin geldanamycin was made with complete selectivity from the 1,4-dihydroquinone generated from a 1,4-bis-methoxymethyl (MOM) ether intermediate. Palladium catalysis with air gave the desired product in 9