622348-86-1

Downstream Products

• 620165-94-8 trans-3-amino-1-benzyl-4-methylpyrrolidine 
• 229322-79-6 (3R,4R)-1-Benzyl-4-methyl-pyrrolidine-3-carbonitrile 
• 137172-67-9 (3R,4S)-N-benzyl-3-azido-4-methylpyrrolidine 

Relevant academic research and scientific papers

Stereocontrolled dopamine receptor binding and subtype selectivity of clebopride analogues synthesized from aspartic acid

Employing the achiral 4-aminopiperidine derivative clebopride as a lead compound, chiral analogues were developed displaying dopamine receptor binding profiles that proved to be strongly dependent on the stereochemistry. Compared to the D1 receptor, the t

Enantio- and diastereocontrolled dopamine D1, D2, D3 and D4 receptor binding of N-(3-pyrrolidinylmethyl)benzamides synthesized from aspartic acid

Subreceptor selectivity tuning of N-(3-pyrrolidinyl)benzamides leading to the selective dopamine D3 ligand ent1h and the derivatives 1g and 1e/ent1e which preferably recognize human D2 or D4 receptors, respectively, is described. Binding profiles were con