622398-34-9Relevant academic research and scientific papers
Light and reductive dual stimuli-responsive PEI nanoparticles: "aND" logic response and controllable release
Huang, Qi,Liu, Tao,Bao, Chunyan,Lin, Qiuning,Ma, Meixin,Zhu, Linyong
, p. 3333 - 3339 (2014)
"AND" logic responsive polyetherimide (PEI)-based polymers PENS were constituted by attaching the photoresponsive o-nitrobenzyl phototrigger and reductive responsive disulfide linker to the polymer PEI. This dual-responsive system maintained micelle-like assembly upon single photo or reductive stimuli. The disassembly only occurred when photo and reductive signals were input at the same time. This smart system was therefore applied as a carrier for the controlled release of the anti-cancer drug doxorubicin (DOX), which exhibited effective release only when UV irradiation and GSH reduction were applied simultaneously. the Partner Organisations 2014.
