62285-43-2 Usage
Uses
Used in Pharmaceutical Applications:
MeCDN is used as a pharmaceutical agent for its ability to release nitric oxide, which plays a crucial role in various physiological processes. Nitric oxide is involved in the regulation of blood flow, immune response, and neurotransmission, among other functions. The controlled release of nitric oxide from MeCDN can be utilized to target specific conditions or diseases where nitric oxide dysregulation is a factor.
Used in Research Applications:
MeCDN is used as a research tool for studying nitric oxide release in biological systems. Its unique chemical structure allows researchers to investigate the mechanisms and pathways involving nitric oxide, which can lead to a better understanding of its role in various physiological and pathological processes. This knowledge can be applied to develop new therapeutic strategies and interventions for conditions related to nitric oxide dysregulation.
Used in Drug Delivery Systems:
In the field of drug delivery, MeCDN can be employed as a carrier for the controlled release of nitric oxide. Its reactivity and ability to release nitric oxide under specific conditions make it a promising candidate for the development of novel drug delivery systems. These systems can be designed to target specific tissues or cells, providing a more precise and effective treatment approach for various medical conditions.
Used in Biomedical Applications:
MeCDN's potential use in the biomedical field lies in its ability to release nitric oxide, which has been shown to have various effects on cell signaling and function. This property can be harnessed for the development of new therapies and treatments for a range of conditions, including cardiovascular diseases, inflammatory disorders, and neurological disorders. Additionally, MeCDN's unique chemical structure and reactivity make it an interesting subject for further research and development in the biomedical field.
Check Digit Verification of cas no
The CAS Registry Mumber 62285-43-2 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 6,2,2,8 and 5 respectively; the second part has 2 digits, 4 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 62285-43:
(7*6)+(6*2)+(5*2)+(4*8)+(3*5)+(2*4)+(1*3)=122
122 % 10 = 2
So 62285-43-2 is a valid CAS Registry Number.
62285-43-2Relevant academic research and scientific papers
α-Diazophosphonic Acids as Potential Photoaffinity Labeling Reagents: Synthesis, Stability, and Photochemistry
Bartlett, Paul A.,Carruthers, Nicholas I.,Winter, Beat M.,Long, Karen P.
, p. 1284 - 1291 (2007/10/02)
A series of α-diazophosphonic acid salts 2-, i-Pr2O3PCN2PO32-, and RR'NCOCN2PO32- > have been synthesized by diazo transfer to a diester precursor followed by ester cleavage with trimethylsilyl bromide.These compounds show disparate stabilities: the sulfamoyl- and phosphono-substituted derivatives decompose slowly even at pH 6.0 (21 deg C, 0.2 M phosphate buffer; t1/2 ca. 5 h), whereas the N,N-dimethylcarbamoyl-substituted analogue decomposes rapidly even at pH 9.0 (t1/2 ca. 40 min).For all three derivatives the decomposition reaction involves initial loss of the PO32- group to give the neutral diazo compound, ZCHN2.The photochemical behavior of the α-diazophosphonic diester precursors ZCN2PO3Me2 and the dianions ZCN2PO32- (Z=Et2NSO2 and i-Pr2O3P) was also investigated by using light of λ > 300 nm.In alcohol or water as solvent, the neutral esters undergo the expected hydroxyl insertion and photoreduction reactions.In contrast, on photolysis in methanol, the anions undergo neither of these reactions; the major products appear to be those of 1,2-migration of one of the phosphate oxygens, leading to the α-hydroxy monoesters ZCHOHPO3Me-.This represents the first report of a photochemical study of a diazo compound with an anionic substituent.Although it is also the first example of formal Wolff rearrangement of an oxygen substituent from phosphorus to an adjacent carbene, we suggest that the migration proceeds via an oxaphosphirane intermediate instead of the classical Wolff-type mechanism.Unfortunately, the intervention of this transformation means that α-diazophosphonate dianions are unlikely to be useful as photoaffinity labeling reagents.
