62290-17-9

Usage

Uses

Used in Organic Synthesis:
Ethyl 3-(bromomethyl)benzoate is used as a reagent in organic synthesis for the introduction of the bromomethyl group into various organic molecules. This property makes it a valuable component in the creation of a wide range of chemical compounds.
Used in Pharmaceutical Production:
In the pharmaceutical industry, Ethyl 3-(bromomethyl)benzoate is utilized in the synthesis of various drugs. Its ability to introduce the bromomethyl group aids in the development of new medicinal compounds with specific therapeutic properties.
Used in Agrochemical Production:
Ethyl 3-(bromomethyl)benzoate also finds application in the agrochemical sector, where it is employed in the production of pesticides and other agricultural chemicals. Its role in these processes contributes to the development of effective solutions for crop protection and enhancement of agricultural yields.
Safety Precautions:
Given its flammable nature and potential to cause skin and eye irritation, it is crucial to handle Ethyl 3-(bromomethyl)benzoate with care. Proper protective equipment should be worn during its use, and it should be stored in a secure, cool, and dry environment, away from sources of heat and ignition to prevent accidents and ensure safe usage.

InChI:InChI=1/C10H11BrO2/c1-2-13-10(12)9-5-3-4-8(6-9)7-11/h3-6H,2,7H2,1H3

Upstream product

• 1711-06-4 3-Methylbenzoyl chloride 
• 99-04-7 m-Toluic acid 
• 64-17-5 ethanol 
• 209743-33-9 3-(bromomethyl)benzoyl bromide 
• 120-33-2 ethyl 3-methylbenzoate 
• 6515-58-8 3-bromomethylbenzoic acid 

Downstream Products

• 33745-47-0 3-formyl-benzoic acid ethyl ester 
• 10036-18-7 <3-Ethoxycarbonyl-benzyl>-malonsaeure-diethylester 
• 143426-62-4 ethyl 3-<(1H-imidazol-1-yl)methyl>benzoate 
• 108836-54-0 3-[2-Imidazol-1-yl-1-(4-methoxy-benzyloxymethyl)-ethoxymethyl]-benzoic acid ethyl ester 
• 112000-44-9 3-(Ethoxycarbonyl)-N-<3-(ethoxycarbonyl)benzyl>-N-(4-methylphenylsulfonyl)anilin 
• 79026-14-5 diethyl (3-carbethoxybenzyl)phosphonate 
• 672883-50-0 ethyl 3-[(3S)-3-(3-cyclopentyloxy-4-methoxyphenylcarboxamido)-2,5-dioxoazolan-1-ylmethyl]benzoate 
• 127356-55-2 3-(carbethoxy)benzyltributyltin 
• 205759-43-9 C₂₀H₂₂O₄ 

Relevant academic research and scientific papers

A 4 + 4 strategy for synthesis of zeolitic metal-organic frameworks: An indium-MOF with SOD topology as a light-harvesting antenna

A zeolitic metal-organic framework with a SOD topology, (Et 2NH2)[In(BCBAIP)]·4DEF·4EtOH (H 4BCBAIP: 5-(bis(4-carboxybenzyl)amino)isophthalic acid) (1), has been constructed by a 4 + 4 synthetic strategy from tetrahedral organic building units and In3+ ions. Compound 1 could adsorb organic dyes and be used as a light-harvesting antenna.

Antiproliferative activities of a library of hybrids between indanones and HDAC inhibitor SAHA and MS-275 analogues

New compounds derived from inhibitors of histone deacetylases (HDACs) have been synthesized and their antiproliferative activities towards non small lung cancer cell line H661 evaluated. Their design is based on hybrids between indanones to limit conformational mobility and other known HDAC inhibitors (SAHA, MS-275). The synthesis of these new derivatives was achieved by alkylation of appropriate indanones to introduce the side chain bearing a terminal ester group, the latter being a precursor of hydroxamic acid and aminobenzamide derivatives. These new analogues were found to be moderately active to inhibit H661 cell proliferation.

Vitamin d analogues

Compounds of the formula I wherein X represents hydrogen or hydroxy; R1 and R2, which may be the same or different, represent hydrogen, (C1-C4)alkyl optionally substituted with one hydroxyl group or one or more fluorine atoms, or, together with the carbon atom to which they are attached, R1 and R2 form a (C3-C5)carbocyclic ring; R3 represents (C1-C4)alkyl, (C1-C4)alkoxy or a halogen atom, such as fluorine, chlorine, bromine, or iodine, and in-vivo hydrolyzable esters thereof with pharmaceutically acceptable acids, may be used in the prophylaxis and/or treatment of dieases characterized by abnormal cell differentiation and/or cell proliferation.

Macrocyclic Hydrocarbons with Rigid and Flexible Building Blocks

We report the synthesis of a series of new hydrocarbon macrocycles. Following the dithia-phane route, four large rings 3-6 of the cyclophane type containing different numbers of ring atoms were prepared confirming the general applicability of this route compared to alternative macrocyclizations. Cycle 3 is the hydrocarbon analogue to the tetralactam and the sulfone amide macrocycles 1 and 2 used in many rotaxane syntheses. The macrocycles synthesized here are supposed to be uselful as wheels in the slipping approach to rotaxanes to further establish a reference system for the cavity size of cyclic compounds by comparing them to certain complemenatry blocking groups. The x-ray data obtained of the macrocycles 3, 5, and 6 reveal the cavity shape and size in solid state.

Synthesis and structure-activity relationships of stilbene retinoid analogs substituted with heteroaromatic carboxylic acids

Retinoids elicit biological responses by activating a series of nuclear receptors. Six retinoid receptors belonging to two families are currently known: retinoic acid receptors (RAR(α,β,andγ)) and retinoid X receptors (RXR(α,β,andγ)). Stilbene retinoid an