62302-28-7

Usage

Uses

Used in Organic Synthesis:
4-Pyridine methanol hydrochloride is utilized as a reagent in organic synthesis for its ability to facilitate various chemical reactions, contributing to the formation of complex organic molecules.
Used in Pharmaceutical Industry:
In the pharmaceutical sector, 4-Pyridine methanol hydrochloride serves as a crucial intermediate. It aids in the synthesis of active pharmaceutical ingredients, playing a pivotal role in the development of new medications.
Used in Agrochemical Production:
4-Pyridine methanol hydrochloride is employed in the manufacturing of agrochemicals, where it contributes to the creation of compounds that protect crops from pests and diseases, thereby ensuring agricultural productivity.
Safety Considerations:
Given its classification as a hazardous substance, 4-Pyridine methanol hydrochloride necessitates careful handling and adherence to strict safety guidelines to mitigate potential risks associated with its use.

InChI:InChI=1/C6H7NO.ClH/c8-5-6-1-3-7-4-2-6;/h1-4,8H,5H2;1H

Upstream product

• 872-85-5 pyridine-4-carbaldehyde 
• 46721-93-1 pyridin-4-ylmethyl benzoate 

Downstream Products

• 1822-51-1 4-picolylchloride hydrochloride 
• 102577-97-9 C₁₈H₂₁N₅O₂S 
• 102564-86-3 4-[2-(3-Methyl-thioureido)-ethylsulfanylmethyl]-2H-pyridine-1-carboxylic acid phenyl ester 
• 102564-82-9 4-[2-(3-Methyl-ureido)-ethylsulfanylmethyl]-2H-pyridine-1-carboxylic acid phenyl ester 

Relevant academic research and scientific papers

Controlling chemoselective transformations of 4-acylpyridines via a Pd-C catalytic hydrodechlorination-hydrogenation

A novel Pd-C catalytic hydrodechlorination-hydrogenation was developed for a multi-step one-pot transformation of 4-acylpyridines. Under the selected conditions, 4-benzoylpyridines and 4-alkanoylpyridines were chemoselectively converted into the corresponding 4-benzylpiperidine hydrochlorides and α-alkyl-4-piperidinemethanol hydrochlorides, respectively. This catalytic method was performed simply by an addition of 1 equiv of ClCH 2CHCl2 to the conventional hydrogenation system and directly gave the crystalline piperidine hydrochlorides in practical quantitative yields.

Hydroxymethylations of aryl halides by Pd-catalyzed cross-couplings with (benzoyloxy)methylzinc iodide - Scope and limitations of the reaction

Palladium-catalyzed cross-coupling reactions of (benzoyloxymethyl)zinc iodide with diverse (het)aryl halides leading to (benzoyloxymethyl)(het)arenes were studied to define the scope of this reaction. It has been found that this reaction is only applicable for electron-deficient aryl halides and the most efficient it is for 2-halopyridines and 4-halopyrimidines. Deprotection of the intermediates gives (hydroxymethyl)pyridines and -pyrimidines in high yields. Georg Thieme Verlag Stuttgart.