623172-50-9Relevant articles and documents
Synthesis of new 3-alkoxy-7-amino-4-chloro-isocoumarin derivatives as new β-amyloid peptide production inhibitors and their activities on various classes of protease
Bihel, Frederic,Quelever, Gilles,Lelouard, Hugues,Petit, Agnes,Da Costa, Cristine Alves,Pourquie, Olivier,Checler, Frederic,Thellend, Annie,Pierre, Philippe,Kraus, Jean-Louis
, p. 3141 - 3152 (2007/10/03)
A series of new 7-substituted-4-chloro-3-alkoxy isocoumarin derivatives were synthesized and evaluated as inhibitors of representative classes of proteases: serine protease (α-chymotrypsin, trypsin), cysteine protease (Caspase-3), and aspartyl protease (H
