623175-24-6Relevant academic research and scientific papers
NAPHTHALENE DERIVATIVE
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Paragraph 0360, (2013/06/27)
The present invention provides compounds which can regulate VCP activity. The present invention provides the compound of formula (I) (R is as defined in the description) or oxides, esters, prodrugs, pharmaceutically acceptable salts or solvates thereof. The compounds can regulate VCP activity, and thus are useful for treating VCP-mediated diseases such as neurodegenerative diseases.
Mapping the kinase domain of janus kinase 3
Adams, Christopher,Aldous, David J.,Amendola, Shelley,Bamborough, Paul,Bright, Colin,Crowe, Sarah,Eastwood, Paul,Fenton, Garry,Foster, Martyn,Harrison, Trevor K. P.,King, Sue,Lai, Justine,Lawrence, Christopher,Letallec, Jean-Philippe,McCarthy, Clive,Moorcroft, Neil,Page, Kenneth,Rao, Sudha,Redford, Jane,Sadiq, Shazia,Smith, Keith,Souness, John E.,Thurairatnam, Sukanthini,Vine, Mark,Wyman, Barry
, p. 3105 - 3110 (2007/10/03)
The utilization and impact of parallel synthesis on lead exploration around initial hit oxindole (1) are described. The emergent SAR, analogue design and functional impact will also be detailed.
