62353-80-4

Usage

Uses

Used in Pharmaceutical Industry:
1-Hydroxy-2-carboamino Naphthalene Derivative is used as a pharmaceutical compound for its anti-inflammatory and antioxidant properties. It has the potential to be developed into a therapeutic agent for various inflammatory and oxidative stress-related conditions.
Used in Materials Science:
1-Hydroxy-2-carboamino Naphthalene Derivative is used as a component in the development of fluorescent dyes and polymers. Its unique chemical structure and properties make it suitable for creating novel materials with specific optical and electronic characteristics, which can be applied in various fields such as sensors, imaging, and optoelectronics.
Further research is necessary to explore additional applications and optimize the synthesis and production methods of 1-Hydroxy-2-carboamino Naphthalene Derivative to enhance its potential benefits in various industries.

InChI:InChI=1/C11H9NO2/c12-11(14)9-6-5-7-3-1-2-4-8(7)10(9)13/h1-6,13H,(H2,12,14)

Upstream product

• 38077-69-9 1-hydroxy-2-naphthoyl chloride 
• 86-48-6 1-hydroxy-2-naphthoic acid 
• 408315-11-7 2-cyano-naphthalene-1-sulfonic acid 

Relevant academic research and scientific papers

Synthesis and structure activity relationship studies of benzothieno[3,2-b]furan derivatives as a novel class of IKKβ inhibitors

As a novel class of IKKβ inhibitors, a series of tricyclic furan derivatives was designed and synthesized based on the structure of known thiophene IKKβ inhibitors. Among the various fused furan derivatives synthesized, a benzothieno[3,2-b]furan derivative 13a displayed potent inhibitory activity towards IKKβ in enzymatic and cellular assays. The potent inhibitory activity originates from an intramolecular non-bonded S...O interaction which was confirmed by the X-ray structure of JNK3 with 16k. The introduction of further substituents on the core structure led to the discovery of the 6-alkoxy derivatives, which possessed a comparable IKKβ inhibitory activity to 13a and an improved metabolic stability. Among these, appropriately lipophilic compounds 16a, h, i, and 13g (logD>2) were found to possess good oral bioavailability.

Photochromatic substances

Disclosed are adamantaneospiroheteroaromaticpyrans and adamantanospiro (1.3)oxazines of the general formula STR1 whereby R0 is a substituent from the series H, halogen, O-alkyl, N-alkyl, R1 -R4 : is a substituent from the series H, alkyl, aryl, subst. phenyl, naphthyl, heteroaryl, OH, alkoxy (C1 -C4), halogen, alkylamino, dialkylamino, cyan and trifluormethyl, or R1 and R2 or R3 and R4 or R2 and R3 are constituents of a condensed aromatic or heteroaromatic ring or an alkane ring with 4-8 C-atoms.