623547-31-9

Upstream product

• 623547-29-5 8-chloro-N-1-[(1R,2S,3R,4R)-2,3-isopropylidenedioxy-4-(hydroxymethyl)cyclopentyl]-5'-O-(tert-butyldimethylsilyl)-2',3'-O-isopropylideneadenosine 
• 623547-28-4 2-chloro-5-(methoxymethyleneamino)-1-[5-O-(tert-butyldimethylsilyl)-2,3-O-isopropylidene-β-D-ribofuranosyl]imidazole-4-nitrile 
• 623547-27-3 2-chloro-5-amino-1-[5-O-(tert-butyldimethylsilyl)-2,3-O-isopropylidene-β-D-ribofuranosyl]imidazole-4-nitrile 
• 132342-52-0 ((3aR,4R,6R,6aS)-6-amino-2,2-dimethyltetrahydro-3aH-cyclopenta[d][1,3]dioxol-4-yl)methanol 
• 623547-30-8 8-chloro-N-1-[(1R,2S,3R,4R)-2,3-isopropylidenedioxy-4-[(5-monomethoxytrityl)oxymethyl]cyclopentyl]-5'-O-(tert-butyldimethylsilyl)-2',3'-O-isopropylideneadenosine 

Downstream Products

• 623547-32-0 8-chloro-N-1-[(1R,2S,3R,4R)-2,3-isopropylidenedioxy-4-[(5-monomethoxytrityl)oxymethyl]cyclopentyl]-5'-O-[bis(phenylthio)phosphoryl]-2',3'-O-isopropylideneadenosine 
• 623547-33-1 8-chloro-N-1-[(1R,2S,3R,4R)-2,3-isopropylidenedioxy-4-(hydroxymethyl)cyclopentyl]-5'-O-[bis(phenylthio)phosphoryl]-2',3'-O-isopropylideneadenosine 

Relevant academic research and scientific papers

Convergent Synthesis and Unexpected Ca2+-Mobilizing Activity of 8-Substituted Analogues of Cyclic ADP-Carbocyclic-Ribose, a Stable Mimic of the Ca2+-Mobilizing Second Messenger Cyclic ADP-Ribose

Cyclic ADP-carbocyclic-ribose (cADPcR, 2) is a biologically and chemically stable equivalent of cyclic ADP-ribose (cADPR, 1), a Ca2+-mobilizing second messenger. In this study, a series of 8-substituted analogues of cADPcR, namely the 8-chloro