623561-69-3Relevant academic research and scientific papers
Dimerization Inhibitors of HIV-1 Protease Based on a Bicyclic Guanidinium Subunit
Breccia, Perla,Boggetto, Nicole,Pérez-Fernández, Ruth,Van Gool, Michiel,Takahashi, Masayuki,René, L?ic,Prados, Pilar,Badet, Bernard,Reboud-Ravaux, Michèle,De Mendoza, Javier
, p. 5196 - 5207 (2003)
Original inhibitors of HIV-1 protease based on a chiral bicyclic guanidinium scaffold linked to short peptidic mimics of the terminal protease sequences and to a lipophilic group were designed. These inhibitors prevent dimerization of the native protease
