623562-27-6

Basic information

• Product Name: t-butyl 6-N-butylamin-3-aminopyridin-4-yl carbamate
• CAS NO: 623562-27-6
• Molecular Weight: 280.37
• Mol File: 623562-27-6.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: t-butyl 6-N-butylamin-3-aminopyridin-4-yl carbamate(CAS DataBase Reference)
• NIST Chemistry Reference: t-butyl 6-N-butylamin-3-aminopyridin-4-yl carbamate(623562-27-6)
• EPA Substance Registry System: t-butyl 6-N-butylamin-3-aminopyridin-4-yl carbamate(623562-27-6)

Safety Data

• Hazardous Substances Data: 623562-27-6(Hazardous Substances Data)

Upstream product

• 623562-22-1 (3-nitro-pyridin-4-yl)-carbamic acid tert-butyl ester 
• 98400-69-2 N-(4-pyridyl) t-butyl carbamate 
• 623562-24-3 t-butyl 2-N-butylamin-5-nitropyridin-4-yl carbamate 

Relevant articles and documents

Preparation of substituted 1,3-dihydro-2H-imidazo[4,5-c]pyridin-2-ones

A new synthetic route to 6-substituted-imidazo[4,5-c]pyridin-2-ons from 4-aminopyridine has been investigated. 4-Aminopyridine protected as alkyl carbamates were nitrated with dinitrogen pentoxide to the corresponding methyl, i-propyl and t-butyl 3-nitropyridin-4-yl carbamates (5a-c) in 51-63% yields. Attempts to substitute these in the 6-position by the ONSH and the VNS techniques succeeded with butylamine and the t-butyl carbamate 9. From the methyl or t-butyl 3-nitropyridin-4-yl carbamates 5a, 5c 1,3-dihydro-2H-imidazo[4,5-c]pyridin-2-one (1) was formed in 73 and 39% yields, respectively. t-Butyl 6-N-butylamin-3-aminopyridin-4-yl carbamate (6) gave 6-butylamino-1,3-dihydro-2H-imidazo[4,5-c]pyridin-2-one (7) in 53% yield.