623564-42-1

Basic information

• Product Name: 8H-Imidazo[2,1-c][1,4]oxazine-2-carboxaldehyde, 5,6-dihydro- (9CI)
• Synonyms: 8H-Imidazo[2,1-c][1,4]oxazine-2-carboxaldehyde, 5,6-dihydro- (9CI);5,6-Dihydro-8H-imidazo[2,1-c][1,4]oxazine-2-carboxaldehyde;5,6-dihydro- (9CI);6,8-Dihydro-5H-imidazo[2,1-c]-[1,4]oxazine-2-carbaldehyde
• CAS NO: 623564-42-1
• Molecular Formula: C₇H₈N₂O₂
• Molecular Weight: 152.15062
• Product Categories: ALDEHYDE;AMINETERTIARY;Intermediates;Heterocycles
• Mol File: 623564-42-1.mol
• Article Data: 5

Chemical Properties

• Boiling Point: 413.696 °C at 760 mmHg
• Flash Point: 203.996 °C
• Appearance: /
• Density: 1.417 g/cm³
• Vapor Pressure: 0mmHg at 25°C
• Refractive Index: 1.646
• Storage Temp.: under inert gas (nitrogen or Argon) at 2-8°C
• CAS DataBase Reference: 8H-Imidazo[2,1-c][1,4]oxazine-2-carboxaldehyde, 5,6-dihydro- (9CI)(CAS DataBase Reference)
• NIST Chemistry Reference: 8H-Imidazo[2,1-c][1,4]oxazine-2-carboxaldehyde, 5,6-dihydro- (9CI)(623564-42-1)
• EPA Substance Registry System: 8H-Imidazo[2,1-c][1,4]oxazine-2-carboxaldehyde, 5,6-dihydro- (9CI)(623564-42-1)

Safety Data

• Hazardous Substances Data: 623564-42-1(Hazardous Substances Data)

Usage

General Description

8H-Imidazo[2,1-c][1,4]oxazine-2-carboxaldehyde, 5,6-dihydro- (9CI) is a chemical compound with the molecular formula C9H7NO2. It is a heterocyclic compound containing an imidazo[2,1-c][1,4]oxazine ring system with a carboxaldehyde functional group. 8H-Imidazo[2,1-c][1,4]oxazine-2-carboxaldehyde, 5,6-dihydro- (9CI) has potential applications in pharmaceuticals, as it exhibits biological activities such as anti-proliferative and anticancer properties. It can also be used as a chemical intermediate in the synthesis of other organic compounds. Additionally, it may have uses in the field of materials science and chemical research due to its unique structure and properties.

InChI:InChI=1/C7H8N2O2/c10-4-6-3-9-1-2-11-5-7(9)8-6/h3-4H,1-2,5H2

Upstream product

• 623564-41-0 morpholin-3-ylideneamine hydrochloride 
• 19263-02-6 2-bromo-3-hydroxypropenal 
• 1096418-58-4 C₉H₁₂N₂O₃ 
• 747408-16-8 morpholin-3-ylideneamine 
• 155272-73-4 2-bromo-3-(1-methylethoxy)-2-propenal 

Downstream Products

• 1096418-62-0 C₂₀H₁₇BrN₄O₇S 
• 623906-31-0 (5R)-6-[acetoxy-(5,6-dihydro-8H-imidazo[2,1-c][1,4]oxazin-2-yl)methyl]-6-bromo-7-oxo-4-thia-1-azabicyclo[3.2.0]hept-2-ene-2-carboxylic acid para-nitrobenzyl ester 
• 1428968-63-1 2-(6,8-dihydro-5H-imidazo[2,1-c][1,4]oxazin-2-yl)-1-(1H-indol-3-yl)-2-((3-methoxyphenyl)amino)ethanone 

Relevant articles and documents

Processes For Preparing Bicyclic Oxazine Carboxaldehyde and Beta-Lactamase Inhibitors

The invention relates to processes for the preparation of the bicyclic oxazine carboxaldehyde Compound 1: The invention also relates to the use of Compound 1 in the preparation of □-lactamase inhibitors.

Bicyclic 6-alkylidene-penems as class-D beta-lactamases inhibitors

This invention relates to certain bicyclic 6-alkylidene penems which act as a inhibitor of class-D enzymes. β-Lactamases hydrolyze β-lactam antibiotics, and as such serve as the primary cause of bacterial resistance. The compounds of the present invention when combined with β-lactam antibiotics will provide an effective treatment against life threatening bacterial infections. In accordance with the present invention there are provided compounds of general formula I or a pharmaceutically acceptable salt or in vivo hydrolyzable ester R5 thereof: wherein: One of A and B denotes hydrogen and the other an optionally substituted fused bicyclic heteroaryl group; and X═O or S.

BICYCLIC 6-ALKYLIDENE-PENEMS AS ?-LACTAMASES INHIBITORS

The present invention provides a compound of Formula (I), pharmaceutical compositions and the use thereof for the treatment of bacterial infection or disease in a patient in need thereof.