623565-58-2

Basic information

• Product Name: 4H-Pyrazolo[5,1-c][1,4]oxazine-2-methanol, 6,7-dihydro-
• Synonyms: 4H-Pyrazolo[5,1-c][1,4]oxazine-2-methanol, 6,7-dihydro-;(6,7-dihydro-4H-pyrazolo[5,1-c][1,4]oxazin-2-yl)methanol
• CAS NO: 623565-58-2
• Molecular Formula: C₇H₁₀N₂O₂
• Molecular Weight: 154.17
• Mol File: 623565-58-2.mol
• Article Data: 9

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 4H-Pyrazolo[5,1-c][1,4]oxazine-2-methanol, 6,7-dihydro-(CAS DataBase Reference)
• NIST Chemistry Reference: 4H-Pyrazolo[5,1-c][1,4]oxazine-2-methanol, 6,7-dihydro-(623565-58-2)
• EPA Substance Registry System: 4H-Pyrazolo[5,1-c][1,4]oxazine-2-methanol, 6,7-dihydro-(623565-58-2)

Safety Data

• Hazardous Substances Data: 623565-58-2(Hazardous Substances Data)

Usage

General Description

4H-Pyrazolo[5,1-c][1,4]oxazine-2-methanol, 6,7-dihydro- is a chemical compound with the molecular formula C8H9N3O2. It is a heterocyclic compound with a pyrazole and oxazine ring fused together. The presence of a hydroxyl group at the 2-position of the oxazine ring makes it a methanol derivative. 4H-Pyrazolo[5,1-c][1,4]oxazine-2-methanol, 6,7-dihydro- may have potential pharmacological properties due to its structure, and further research could be conducted to explore its potential applications in the fields of medicine and drug development.

Upstream product

• 623565-57-1 ethyl 6,7-dihydro-4H-pyrazolo[5,1-c][1,4]oxazine-2-carboxylate 

Downstream Products

• 623565-60-6 4-nitrobenzyl (5R)-6-[(acetyloxy)(6,7-dihydro-4H-pyrazolo[5,1-c][1,4]oxazin-2-yl)methyl]-6-bromo-7-oxo-4-thia-1-azabicyclo[3.2.0]hept-2-ene-2-carboxylate 
• 623565-59-3 6,7-dihydro-4H-pyrazolo[5,1-c][1,4]oxazine-2-carbaldehyde 

Relevant articles and documents

Polyheterocyclic substituted pyrimidines or pyridylamine derivatives Composition and medical application thereof

The invention discloses a polycyclic substituted pyrimidine or pyridine amine derivative, and the structure is shown in a formula (I). The invention further discloses a pharmaceutically acceptable salt of the derivative, a solvate, a stereoisomer, a prodrug, a pharmaceutical composition and and an application thereof in medicine. The compounds of the present invention have significant adenosine A. 2A Receptor and/or adenosine A2B The receptor antagonism activity is very practical.

MACROCYCLIC INDOLES AS MCL-1 INHIBITORS

Disclosed is compound of formula I and the pharmaceutically acceptable salts and solvates thereof, wherein R, R1a, R1b, R1h, L1, L2, L3, ?, ?, ? are as defined as set forth in the specification. Disclosed is compound of formula I for use to treat a condition or disorder responsive to Mcl-1 inhibition such as cancer.

Big ring indole used as MCL-1 inhibitor

The invention provides a compound represented by a formula (I) and a pharmaceutical salt and solvate thereof. In the formula (I), the definitions of R, R1a, R1b, R1h, L1, L2, and L3 are shown in the description. The invention also provides a compound represented by the formula (I), and the compound can be used to treat disease or disorder related with MCL-1 inhibition, such as cancers.