62357-69-1

Basic information

• Product Name: (1R,2R,3R,5R)-3-(6-chloro-9H-purin-9-yl)-5-(hydroxymethyl)cyclopentane-1,2-diol
• CAS NO: 62357-69-1
• Molecular Formula: C₁₁H₁₃ClN₄O₃
• Molecular Weight: 284.6989
• Mol File: 62357-69-1.mol
• Article Data: 1

Chemical Properties

• Boiling Point: 544°C at 760 mmHg
• Flash Point: 282.8°C
• Density: 1.89g/cm³
• Vapor Pressure: 1.15E-12mmHg at 25°C
• Refractive Index: 1.827
• CAS DataBase Reference: (1R,2R,3R,5R)-3-(6-chloro-9H-purin-9-yl)-5-(hydroxymethyl)cyclopentane-1,2-diol(CAS DataBase Reference)
• NIST Chemistry Reference: (1R,2R,3R,5R)-3-(6-chloro-9H-purin-9-yl)-5-(hydroxymethyl)cyclopentane-1,2-diol(62357-69-1)
• EPA Substance Registry System: (1R,2R,3R,5R)-3-(6-chloro-9H-purin-9-yl)-5-(hydroxymethyl)cyclopentane-1,2-diol(62357-69-1)

Safety Data

• Hazardous Substances Data: 62357-69-1(Hazardous Substances Data)

Upstream product

• 13190-82-4 (+/-)-(1RS,2SR,3RS,5RS)-3-(5-amino-6-chloro-pyrimidin-4-yl-amino)-5-hydroxymethyl-cyclopentane-1,2-diol 
• 122-51-0 orthoformic acid triethyl ester 

Relevant articles and documents

Biocatalytical Transformations- VI. The 4-Acetamido-cyclopent-2-ene Carboxylate Route Revisited: Synthesis of (+)- and (-)-Aristeromycin

Enantiomerically pure (+)-as well as (-)-aristeromycin can be synthesized starting from (+)- or (-)-butyl (or hexyl) 4-acetamido-cyclopent-2-ene carboxylate; these carboxylates are easily obtained from their corresponding racemates by hydrolysis with the lipase from Candida rugosa.