623573-80-8

Basic information

• Product Name: [2-benzyloxymethyl-4-(2,4-difluoro-phenyl)-pent-4-enyl]-carbamic acid tert-butyl ester
• CAS NO: 623573-80-8
• Molecular Weight: 417.496
• Mol File: 623573-80-8.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: [2-benzyloxymethyl-4-(2,4-difluoro-phenyl)-pent-4-enyl]-carbamic acid tert-butyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: [2-benzyloxymethyl-4-(2,4-difluoro-phenyl)-pent-4-enyl]-carbamic acid tert-butyl ester(623573-80-8)
• EPA Substance Registry System: [2-benzyloxymethyl-4-(2,4-difluoro-phenyl)-pent-4-enyl]-carbamic acid tert-butyl ester(623573-80-8)

Safety Data

• Hazardous Substances Data: 623573-80-8(Hazardous Substances Data)

Upstream product

• 623573-79-5 1-(3-Azidomethyl-4-benzyloxy-1-methylene-butyl)-2,4-difluoro-benzene 
• 623573-78-4 2-benzyloxymethyl-4-(2,4-difluoro-phenyl)-pent-4-en-1-ol 
• 623573-88-6 5-[2-(2,4-difluoro-phenyl)-allyl]-2-phenyl-[1,3]dioxane 
• 165115-73-1 2-[2-(2,4-difluorophenyl)-2-propene-1-yl]-1, 3-propanediol 
• 1125-88-8 benzaldehyde dimethyl acetal 
• 24424-99-5 di-tert-butyl dicarbonate 
• 623573-89-7 2-benzyloxymethyl-4-(2,4-difluoro-phenyl)-pent-4-enylamine 

Relevant articles and documents

A highly stereoselective approach to novel 2,2,4-trisubstituted pyrrolidines by halocylization: Key intermediates towards syntheses of nitrogen analogs of Noxafil

A convenient synthesis of novel 2,2,4-trisubstituted pyrrolidines via stereoselective 5-exo iodocyclization of the 2,2-disubstituted olefins 8 and 9 is described. Single crystal X-ray analysis of the oxazolidinone 15 confirmed the relative stereochemistry in this cyclization. As observed earlier in the formation of 2,2,4-trisubstituted tetrahydrofurans, the presence of a bulky aryl substituent on the olefin appears to direct the stereochemical outcome of these halocyclizations.