623583-10-8

Basic information

• Product Name: [(2S)-4,4-difluoropyrrolidin-2-yl]methanol hydrochloride
• Synonyms: [(2S)-4,4-difluoropyrrolidin-2-yl]methanol hydrochloride;(S)-(4,4-Difluoropyrrolidin-2-yl)methanol hydrochloride;(S)-2-(Hydroxymethyl)-4,4-difluoropyrrolidine hydrochloride;(S)-(4,4-Difluoropyrrolidin-2-Yl)Methanol Hydrochloride(WX601204)
• CAS NO: 623583-10-8
• Molecular Formula: C5H10ClF2NO
• Molecular Weight: 173.59
• Mol File: 623583-10-8.mol
• Article Data: 0

Chemical Properties

• Appearance: /
• Storage Temp.: under inert gas (nitrogen or Argon) at 2-8°C
• CAS DataBase Reference: [(2S)-4,4-difluoropyrrolidin-2-yl]methanol hydrochloride(CAS DataBase Reference)
• NIST Chemistry Reference: [(2S)-4,4-difluoropyrrolidin-2-yl]methanol hydrochloride(623583-10-8)
• EPA Substance Registry System: [(2S)-4,4-difluoropyrrolidin-2-yl]methanol hydrochloride(623583-10-8)

Safety Data

• Hazardous Substances Data: 623583-10-8(Hazardous Substances Data)

Usage

Description

[(2S)-4,4-difluoropyrrolidin-2-yl]methanol hydrochloride is a chemical compound derived from pyrrolidine, a heterocyclic amine. It features a difluoromethyl group and a hydroxyl group, which contribute to its unique properties and potential applications in various fields. [(2S)-4,4-difluoropyrrolidin-2-yl]methanol hydrochloride is characterized by its stereochemistry, with the "2S" designation indicating the specific arrangement of atoms in the molecule.

Uses

Used in Pharmaceutical Research:
[(2S)-4,4-difluoropyrrolidin-2-yl]methanol hydrochloride is used as a key intermediate in the synthesis of pyrrolotriazines, which are being studied for their potential as pan-Aurora kinase inhibitors and anti-tumor agents. [(2S)-4,4-difluoropyrrolidin-2-yl]methanol hydrochloride plays a crucial role in understanding the structure-activity relationship of these inhibitors, which can help in the development of more effective cancer treatments.
Used in Drug Development:
In the field of drug development, [(2S)-4,4-difluoropyrrolidin-2-yl]methanol hydrochloride is utilized to investigate the pharmacokinetics of pyrrolotriazines. This knowledge is essential for optimizing the drug's absorption, distribution, metabolism, and excretion, ultimately leading to improved therapeutic outcomes for patients with cancer.
Used in Medicinal Chemistry:
Medicinal chemists employ [(2S)-4,4-difluoropyrrolidin-2-yl]methanol hydrochloride as a building block for designing and synthesizing novel compounds with potential therapeutic applications. Its unique structural features make it a valuable tool in the search for new drugs to combat various diseases, including cancer.
Used in Chemical Synthesis:
[(2S)-4,4-difluoropyrrolidin-2-yl]methanol hydrochloride is also used in chemical synthesis for creating a variety of compounds with different applications. Its versatility and reactivity make it a valuable component in the development of new materials and products across various industries.