623584-08-7Relevant academic research and scientific papers
Macrocyclic cis- and trans-bis(α-amino acids) and their intraannular Cu(II) complexes. Conformational in-out dichotomy and crystal packing
Bělohradsky, Martin,Budě?ínsky, Milo?,Císa?ová, Ivana,Dekoj, Václav,Holy, Petr,Závada, Ji?í
, p. 7751 - 7760 (2003)
Macrocyclic bis(α-amino acids) cis- and trans-2a-b were prepared from the selectively protected tris(hydroxymethyl)aminomethane 3. The X-ray structures of the free bis(amino acids) and/or of the corresponding Cu(II) complexes have been determined allowing an unambiguous configurational assessment. At the same time, conformational in-out dichotomy of the functional groups has been demonstrated in the bis(amino acids) as well as in their Cu(II) complexes.
