623586-00-5

Basic information

• Product Name: 1-CBZ-(R)-3-METHYLPIPERAZINE
• Synonyms: 1-CBZ-(R)-3-METHYLPIPERAZINE;4-N-BENZOXYCARBONYL-2-(R)-METHYLPIPERAZINE;4-CBZ-(R)-2-METHYL PIPERAZINE;4-BENZOXYCARBONYL-2-(R)-METHYLPIPERAZINE;(R)-4-CBZ-2-METHYLPIPERAZINE;(3R)-1-Benzyloxycarbonyl-3-methylpiperazine;(R)-4-Benzoxycarbonyl-2-methylpiperazine;(R)-1-CBz-3-methylpiperazine
• CAS NO: 623586-00-5
• Molecular Formula: C₁₃H₁₈N₂O₂
• Molecular Weight: 234.29
• Mol File: 623586-00-5.mol
• Article Data: 1

Chemical Properties

• Boiling Point: 358°C at 760 mmHg
• Flash Point: 170.3°C
• Appearance: /
• Density: 1.105g/cm³
• Vapor Pressure: 2.62E-05mmHg at 25°C
• Refractive Index: 1.53
• Storage Temp.: under inert gas (nitrogen or Argon) at 2–8 °C
• PKA: 8.50±0.40(Predicted)
• CAS DataBase Reference: 1-CBZ-(R)-3-METHYLPIPERAZINE(CAS DataBase Reference)
• NIST Chemistry Reference: 1-CBZ-(R)-3-METHYLPIPERAZINE(623586-00-5)
• EPA Substance Registry System: 1-CBZ-(R)-3-METHYLPIPERAZINE(623586-00-5)

Safety Data

• Hazardous Substances Data: 623586-00-5(Hazardous Substances Data)

Usage

General Description

1-CBZ-(R)-3-METHYLPIPERAZINE is a chemical compound with the molecular formula C14H22N2O2. It is a derivative of piperazine, a heterocyclic compound commonly used in pharmaceuticals and organic synthesis. 1-CBZ-(R)-3-METHYLPIPERAZINE is predominantly used as a building block in the synthesis of various pharmaceutical and agrochemical products. Its carbobenzyloxy (CBZ) protecting group allows for selective modification and functionalization, making it a valuable intermediate in the production of a wide range of organic compounds. 1-CBZ-(R)-3-METHYLPIPERAZINE is also known for its potential application in the development of new drug molecules and in medicinal chemistry research.

InChI:InChI=1/C13H18N2O2/c1-11-9-15(8-7-14-11)13(16)17-10-12-5-3-2-4-6-12/h2-6,11,14H,7-10H2,1H3/t11-/m1/s1

Upstream product

• 75336-86-6 (2R)-methylpiperazine 
• 501-53-1 benzyl chloroformate 

Downstream Products

• 883976-26-9 (R,E)-benzyl 4-(N,N'-(bis(tert-butoxycarbonyl))carbamimidoyl)-3-methylpiperazine-1-carboxylate 

Relevant articles and documents

Vanilloid receptor ligands and their use in treatments

Therapeutic benzimidazoles and compositions containing them, for the treatment of acute, inflammatory and neuropathic pain, dental pain, general headache, migraine, cluster headache, mixed-vascular and non-vascular syndromes, tension headache, general inflammation, arthritis, rheumatic diseases, osteoarthritis, inflammatory bowel disorders, inflammatory eye disorders, inflammatory or unstable bladder disorders, psoriasis, skin complaints with inflammatory components, chronic inflammatory conditions, inflammatory pain and associated hyperalgesia and allodynia, neuropathic pain and associated hyperalgesia and allodynia, diabetic neuropathy pain, causalgia, sympathetically maintained pain, deafferentation syndromes, asthma, epithelial tissue damage or dysfunction, herpes simplex, disturbances of visceral motility at respiratory, genitourinary, gastrointestinal or vascular regions, wounds, burns, allergic skin reactions, pruritus, vitiligo, general gastrointestinal disorders, gastric ulceration, duodenal ulcers, diarrhea, gastric lesions induced by necrotising agents, hair growth, vasomotor or allergic rhinitis, bronchial disorders or bladder disorders.