623586-35-6Relevant academic research and scientific papers
A concise building block approach to a diverse multi-arrayed library of the circumdatin family of natural products
Grieder, Alfred,Thomas, Andrew W.
, p. 1707 - 1711 (2003)
Using a polymer-supported phosphine-mediated intramolecular aza-Wittig reaction in a key step of a reaction sequence a diverse library of benzodiazepine-quinazolinone alkaloids (Circumdatins) has been prepared using a novel modified Eguchi protocol. The multi-arrayed library generation strategy commenced from readily accessible benzodiazepinedione derivatives (and anthranilic acids) and all library members were purified by reverse phase preparative HPLC.
