62371-39-5Relevant academic research and scientific papers
The Direct Conversion of α-Hydroxyketones to Alkynes
Ghiringhelli, Francesca,Nattmann, Lukas,Bognar, Sabine,Van Gemmeren, Manuel
, p. 983 - 993 (2019/01/24)
Alkynes are highly important functional groups in organic chemistry, both as part of target structures and as versatile synthetic intermediates. In this study, a protocol for the direct conversion of α-hydroxyketones to alkynes is reported. In combination with the variety of synthetic methods that generate the required starting materials by forming the central C-C bond, it enables a highly versatile fragment coupling approach toward alkynes. A broad scope for this novel transformation is shown alongside mechanistic insights. Furthermore, the utility of our protocol is demonstrated through its application in concert with varied α-hydroxyketone syntheses, giving access to a broad spectrum of alkynes.
Nickel mdiated Double Bond formation from vic-Dibromides and Ethyl Magnesium Bromide
Malanga, Corrado,Aronica, Laura A.,Lardicci, Luciano
, p. 9189 - 9192 (2007/10/02)
vic-dibromides are quantitaively converted into alkenes by using a catalityc amount of NidppeCl2 in the presence of two molar equivalents of EtMgBr in THF.Stereochemical aspects of the reaction are given.
Furyl compounds, their use as fungicides and their preparation
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, (2008/06/13)
The present invention provides in one aspect a method of combating a fungus at a locus, characterised by treating the locus with a fungicidally effective amount of a compound of general formula I wherein each of R1 and R2 independently represents a hydrog
