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• 623-27-8 terephthalaldehyde, 
• 95-54-5 1,2-diamino-benzene 

Relevant academic research and scientific papers

A ratiometric fluorescent probe for bisulphite anion, employing intramolecular charge transfer

4-(1H-benzimidazol-2-yl)benzaldehyde (1) has been developed as a new ratiometric fluorescent probe for bisulphite, based on the modulation of intramolecular charge transfer (ICT). Upon mixing with bisulphite in aqueous ethanol, an aldehyde-bisulphite adduct was formed and the ICT of the probe was switched off, which resulted in a ratiometric fluorescence response with an enhancement of the ratios of emission intensities at 368 and 498 nm. The detection range of the probe for bisulphite is in the 2.0-200 μmol/L concentration range and the detection limit is 0.4 μmol/L. Probe 1 produces a ratiometric fluorescent response to bisulphite with a marked emission wavelength shift (130 nm) and displays high selectivity for bisulphite over other anions. Copyright

Comparative studies on the absorption and fluorescence responses of hemicyanine to HSO3?, CN?, HS? and ClO?

A fluorescent probe Hcy-Im bearing an indolium-hemicyanine structure was designed and synthesized to compare its responses to four anions, namely HSO3?, CN?, HS? and ClO?. The results disclosed that Hcy-Im reacted with all these four anions in 5% DMSO-PBS buffer with different speeds and spectral changes. Hcy-Im responded to HSO3? markedly quicker than CN? and HS?, and it responded to CN? a little quicker than HS? while the response to ClO? was much slower than the other three anions. The detection limits for these four anions were calculated to be 0.15 μM, 1.32 μM, 2.07 μM and 2.29 μM, respectively. The characteristic conjugated C[dbnd]N+ and C[dbnd]C bonds in Hcy-Im were responsible for the responses towards these four anions via a Michael addition-rearrangement reaction, a 1, 2-addition reaction or an oxidation reaction. These different sensing mechanisms were verified by 1HNMR and HRMS. Thus, it could be inferred that hemicyanine-based fluorescent probe could detect HSO3? sensitively and selectively while the interference of HSO3? should not be neglected when it was used for the detection of CN?, HS? and ClO?. Moreover, as HSO3?, HS? and ClO? are anions endogenously generated in human bodies, enough attention should be paid to the presence of physiological level of these three anions in certain tissues when hemicyanine-based fluorescent probe is applied for the detection of biorelevant analytes in biological samples.

Reaction type benzimidazole fluorescent probe capable of specifically identifying mercury ions as well as preparation method and application thereof

The invention provides a reaction type benzimidazole fluorescent probe ZY13 capable of specifically identifying mercury ions as well as a preparation method and application thereof. The structure of the probe ZY13 is: the probe is a reaction type probe de

BiOCl/FeOCl/SiO2 nanocomposite as an efficient novel catalyst toward the synthesis of 2-aryl-1hbenzimidazoles in mild aerobic condition

BiOCl/FeOCl nanorods composited by SiO2 spherical nanoparticles as a novel nanocatalyst and also it has been synthesized using a co-precipitation procedure. Additionally, its structural along with the catalyst activity have been determined by t

Magnetic nanoparticle-supported DABCO tribromide: A versatile nanocatalyst for the synthesis of quinazolinones and benzimidazoles and protection/deprotection of hydroxyl groups

1,4-Diazabicyclo[2.2.2]octane tribromide supported on magnetic Fe3O4 nanoparticles (MNPs-DABCO tribromide) as a novel heterogeneous tribromide type compound was found to be an efficient and reusable nanocatalyst for the one-pot synthesis of 2-arylquinazolin-4(3H)-ones and 2-aryl-1H-benzo[d]imidazoles through oxidative cyclization of aldehydes with 2-aminobenzamides and 1,2-phenylenediamine, respectively. Also, MNPs-DABCO tribromide catalyzed trimethylsilylation/tetrahydropyranylation and desilylation/depyranylation of a wide variety of alcohols and phenols through changing the solvent medium at room temperature.

Synthesis of 2-substituted benzimidazoles and benzothiazoles using Ag2CO3/Celite as an efficient solid catalyst

An efficient and simple approach for the synthesis of 2-substituted benzimidazoles and benzothiazoles through a coupling of 1,2-phenylenediamines and 2-aminothiophenols with variety of aryl aldehydes in ethanol at 70 °C using Ag2CO3/Celite as solid catalyst is described. The procedure features short reaction time, excellent yields and simple workup.