62409-33-0

Basic information

• Product Name: N-(pyrrole-2-carboxyl)glycine
• Synonyms: N-(pyrrole-2-carboxyl)glycine;methyl 2-(1H-pyrrol-2-ylformamido)acetate
• CAS NO: 62409-33-0
• Molecular Formula: C8H10N2O3
• Molecular Weight: 182.1766
• Mol File: 62409-33-0.mol
• Article Data: 1

Chemical Properties

• Boiling Point: 446.8°C at 760 mmHg
• Flash Point: 224°C
• Appearance: /
• Density: 1.259g/cm³
• Vapor Pressure: 3.55E-08mmHg at 25°C
• Refractive Index: 1.539
• CAS DataBase Reference: N-(pyrrole-2-carboxyl)glycine(CAS DataBase Reference)
• NIST Chemistry Reference: N-(pyrrole-2-carboxyl)glycine(62409-33-0)
• EPA Substance Registry System: N-(pyrrole-2-carboxyl)glycine(62409-33-0)

Safety Data

• Hazardous Substances Data: 62409-33-0(Hazardous Substances Data)

Usage

Uses

Methyl N-[(2-Pyrrolyl)carbonyl]glycinate is an intermediate in the synthesis of N-(1H-pyrrol-2-ylcarbonyl)-Glycine (P834600), used as a diagnostic marker of hyperprolinemia type II.

InChI:InChI=1/C8H10N2O3/c1-13-7(11)5-10-8(12)6-3-2-4-9-6/h2-4,9H,5H2,1H3,(H,10,12)

Upstream product

• 35302-72-8 pyrrol-2-yl trichloromethyl ketone 
• 5680-79-5 glycine ethyl ester hydrochloride 

Relevant articles and documents

One-Pot Friedel-Crafts/Robinson-Gabriel Synthesis of the Indole-Oxazole Scaffold and Its Application to the Synthesis of Breitfussins C, G, and H

The indole-oxazole scaffold is found in a range of biologically active natural products, including the breitfussin family. Divergent methods that provide access to the indole-oxazole template are relatively scarce, which impedes the wider exploration of these natural products and their exciting biological activity. Herein, we describe a highly divergent synthesis of the indole-oxazole scaffold via a one-pot Friedel-Crafts/Robinson-Gabriel synthesis and the application of this methodology to the synthesis of breitfussins C, G, and H.