62421-70-9Relevant articles and documents
Synthetic method of light stabilizer intermediate of 1,2,2,6,6-pentamethyl-4-pipradrol
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Paragraph 0032; 0033; 0039; 0045; 0051; 0062; 0069; 0075, (2018/03/26)
The invention provides a synthetic method of a light stabilizer intermediate of 1,2,2,6,6-pentamethyl-4-pipradrol, and particularly relates to the technical field of light stabilizer preparation. Themethod comprises two step reactions; in the first step, 2,2,6,6-tetramethyl-4-pipradrol and paraformaldehyde are mixed according to a certain proportion and are added into a solvent; stirring is performed for a certain time at the ordinary pressure and a certain reaction temperature, so that the 2,2,6,6-tetramethyl-4-pipradrol completely reacts; then, cooling is performed to reach room temperature; filtering is performed to remove excessive paraformaldehyde; a hydroxymethylated product is obtained; in the second step, a reduction type solid catalyst is charged into a fixed bed reactor; the solvent is added into the reaction liquid; the mixture is continuously introduced into the fixed bed reactor at a certain feeding speed; hydrogen gas is introduced; heating is performed; the reaction liquid continuously flows out from the lower end of the fixed bed reactor; flowing-out reaction liquid is subjected to cooling, gas-liquid separation, liquid filtering, filter liquid solvent steaming removal and purification; the target product is obtained. The synthetic method has the advantages that the preparation is simple and convenient; economic performance and environment-friendly effects areachieved; the product quality is high; the yield is high; the method is suitable for industrial production.