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62423-73-8

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62423-73-8 Usage

Description

3-(2-Bromoacetyl)benzoic acid, also known as o-Bromoacetylbenzoic acid, is a chemical compound with the molecular formula C9H7BrO3. It is a derivative of benzoic acid, featuring an acetyl group attached to the second carbon and a bromine atom attached to the third carbon of the benzene ring. This white to off-white crystalline powder is sparingly soluble in water but readily soluble in organic solvents like ethanol and methanol. Its unique chemical properties make it a versatile intermediate in the synthesis of pharmaceuticals and agrochemicals, as well as a component in various chemical applications.

Uses

Used in Pharmaceutical Industry:
3-(2-Bromoacetyl)benzoic acid is used as a key intermediate in the synthesis of various pharmaceutical compounds. Its unique structure allows for the development of new drugs with specific therapeutic properties, contributing to the advancement of medicine.
Used in Agrochemical Industry:
In the agrochemical sector, 3-(2-Bromoacetyl)benzoic acid serves as an essential building block for the creation of novel agrochemicals. Its chemical reactivity enables the production of effective pesticides and other agricultural chemicals that enhance crop protection and yield.
Used in Organic Synthesis:
3-(2-Bromoacetyl)benzoic acid is utilized as a versatile reagent in organic synthesis. Its ability to participate in various chemical reactions, such as nucleophilic substitution and electrophilic aromatic substitution, makes it a valuable component in the synthesis of complex organic molecules for a wide range of applications.
Used in Chemical Research:
As a chemical compound with distinct properties, 3-(2-Bromoacetyl)benzoic acid is employed in research settings to study reaction mechanisms, explore new synthetic routes, and develop innovative applications in the chemical sciences. Its unique structure and reactivity provide a platform for scientific exploration and discovery.

Check Digit Verification of cas no

The CAS Registry Mumber 62423-73-8 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 6,2,4,2 and 3 respectively; the second part has 2 digits, 7 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 62423-73:
(7*6)+(6*2)+(5*4)+(4*2)+(3*3)+(2*7)+(1*3)=108
108 % 10 = 8
So 62423-73-8 is a valid CAS Registry Number.

62423-73-8SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 18, 2017

Revision Date: Aug 18, 2017

1.Identification

1.1 GHS Product identifier

Product name 3-(2-Bromoacetyl)benzoic acid

1.2 Other means of identification

Product number -
Other names 3-(2-BROMOACETYL)BENZOIC ACID

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:62423-73-8 SDS

62423-73-8Upstream product

62423-73-8Relevant articles and documents

Discovery and structure-activity relationship of the first non-pep tide competitive human glucagon receptor antagonists

Madsen, Peter,Knudsen, Lotte B.,Wiberg, Finn C.,Carr, Richard D.

, p. 5150 - 5157 (2007/10/03)

The first non-peptide competitive human glucagon receptor antagonist, 2-(benzimidazol-2ylthio)-l-(3,4-dihydroxyphenyl)-l-ethanone, NNC 92-1687 (2), is described. This antagonist has a binding affinity of 20 μM (ICso) and a functional Ki = 9.1 μM at the human glucagon receptor. A structure-activity relationship (SAR) was obtained on this compound, and the results show that only the benzimidazole part can be changed without complete loss of affinity. Analogues with tert-butyl or benzyloxy groups in the 5-position of the benzimidazole moiety were found to be equipotent or slightly more potent, all displaying binding affinities around 5-20 μM. Most of the changes to the catechol and the linker gave compounds without any affinity toward the human glucagon receptor. The 3-hydroxy group could, however, in the presence of a 4-hydroxy group be changed to a methoxy or a chloro group while retaining affinity.

Novel thiazole derivatives as inhibitors of superoxide production by human neutrophils: Synthesis and structure-activity relationships

Chihiro,Nagamoto,Takemura,Kitano,Komatsu,Sekiguchi,Tabusa,Mori,Tominaga,Yabuuchi

, p. 353 - 358 (2007/10/02)

Neutrophils have an important role in the self-defense systems of organisms through the production of superoxide. On the other hand, it has been proposed that abnormal amounts of superoxide produced by neutrophils are a serious factor in tissue injury. A series of novel thiazole derivatives was prepared and evaluated inhibitory effect on superoxide production by human neutrophils in vitro. Among these compounds, 6-[2-(3,4- diethoxyphenyl)thiazol-4-yl]-pyridine-2-carboxylic acid (OPC-6535) was selected as one of the most promising compounds. The synthesis and structure- activity relationships of these compounds are reported herein.

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