6244-16-2Relevant academic research and scientific papers
Diisophorone and Related Compounds, Part 27. Nucleophilic Reactions of 1-Halogenodiisophoranes
Kurzer, Frederick,Duffner, C. Richard
, p. 1314 - 1323 (2007/10/02)
The action of nucleophiles on 1-halogenodiisophoranes obtained by several methods from the corresponding 1-hydroxy or 1-alkoxy compounds, replaces their bridgehead 1-halogen by hydroxy, alkoxy or acetoxy groups.The semiquantitative results show that the h
7,10a-Methanocyclooctaindazoles: Diisophoranes Incorporating the Pyrazole Ring System
Kurzer, Frederick,Langer, Stanley S.
, p. 871 - 879 (2007/10/02)
Compounds of the novel 7,10a-methanocyclooctaindazole ring-system 5, 7 are obtained by the action of hydrazines on 1-chloro(or hydroxy)diisophor-2,7-en-3-ones 1-3.Their formulation agrees with their origin and their chemical and spectral characteristics.Analogous syntheses of two comparable ring-systems include the production of a substituted 7,10a-methanocyclooctabenzisoxazole 10 by a facile cyclodehydration of the oxime of diisophorone 9a, and that of the indole-analogue 13 by the action of aniline on diisophorone-1-carboxylic acid 11.
Di-isophorone and Related Compounds. Part 8. 1-Aminodi-isophorane Derivatives
Allen, Anthony A.,Kurzer, Frederick
, p. 617 - 626 (2007/10/02)
The interaction of 1-chlorodi-isophor-2(7)-en-3-one or its 5,11-bisnor-homologue with potassium phthalimide yields the corresponding 1-phthalimido-compounds, which are converted into the 1-amines on treatment with hydrazine, followed by hydrolysis. 1-Aminodi-isophor-2(7)-ene is not accessible by this route, but its N-acyl-derivatives are obtainable directly from 1-hydroxydi-isophor-2(7)-ene by the Ritter reaction; the 3-keto-analogue reacts similarly.Some properties of the novel 1-aminodi-isophoranes are described. - Keywords: Di-isophorones, 1-amino; Tricyclo2,7>tridecanes
Di-isophorone and Related Compounds. Part 5. 2,7-Epoxydi-isophoranes: Oxiran Cleavage by Perchloric Acid
Allen, Anthony A.,Kurzer, Frederick,Morgan, Alan R.
, p. 733 - 737 (2007/10/02)
Perchloric acid slowly converts 2,7-epoxy-1-hydroxydi-isophoran-3-one into 1,4-dihydroxydi-isophor-2(7)-en-3-one, the structure of which is in accord with its alternative formation from 2,7-epoxy-1-hydroxydi-isophorane-3,4-dione by reduction with zinc in
