62445-25-4

Basic information

• Product Name: (S)-2,4-DIHYDROXYBUTYRIC ACID
• Synonyms: (S)-2,4-DIHYDROXYBUTYRIC ACID;(2S)-2,4-Dihydroxybutanoic acid;3-Deoxy-L-glycero-tetronic acid
• CAS NO: 62445-25-4
• Molecular Formula: C₄H₈O₄
• Molecular Weight: 120.1
• Mol File: 62445-25-4.mol
• Article Data: 3

Chemical Properties

• Boiling Point: 412 °C at 760 mmHg
• Flash Point: 217.1 °C
• Appearance: /
• Density: 1.42 g/cm³
• CAS DataBase Reference: (S)-2,4-DIHYDROXYBUTYRIC ACID(CAS DataBase Reference)
• NIST Chemistry Reference: (S)-2,4-DIHYDROXYBUTYRIC ACID(62445-25-4)
• EPA Substance Registry System: (S)-2,4-DIHYDROXYBUTYRIC ACID(62445-25-4)

Safety Data

• Hazardous Substances Data: 62445-25-4(Hazardous Substances Data)

Usage

General Description

(S)-2,4-Dihydroxybutyric acid, also known as (S)-2,4-DHB, is a naturally occurring organic compound that belongs to the class of hydroxybutyric acids. It is a chiral molecule that exists in two enantiomeric forms, with the (S)-enantiomer being the biologically active form. (S)-2,4-DHB is found in certain plant tissues and is a key intermediate in the biosynthesis of vitamin C. It also has antioxidant properties and has been studied for its potential therapeutic effects in the treatment of various diseases, including cancer and neurodegenerative disorders. Its chemical structure makes it an important target for biochemical studies and pharmaceutical research.

Upstream product

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Downstream Products

• 97-67-6 (S)-Malic acid 

Relevant articles and documents

A METHOD OF PRODUCTION OF ２,4-DIHYDROXYBUTYRIC ACID

A method for the preparation of 2,4-dihydroxybutyric acid (2,4-DHB) including the successive steps of converting malate, succinyl-CoA and/or glyoxylate into malyl-CoA, converting malyl-CoA previously obtained into malate-4-semialdehyde, and converting malate-4-semialdehyde into 2,4-DHB using a DHB dehydrogenase.

Synthesis and Nuclear Magnetic Resonance Studies of Some N-Acylated Methyl 4-Amino-4,6-dideoxy-α-D-mannopyranosides

The methyl α-glycosides of 4-amino-4,6-dideoxy-D-mannopyranose (perosamine), N-acylated with either formic, acetic, or (S)-2,4-dihydroxybutanoic acid, have been synthesized.The (1)H and (13)C n.m.r. spectra of these substances and the parent, non-N-acylated glycoside, demonstrated how the chemical shifts are influenced by the N-acylation.The N-formyl derivative occured in two conformations, s-cis and s-trans, and the free-energy barrier between these, 86.9 kJ mol-1, was defined by dynamic n.m.r. spectroscopy.