62455-60-1

Basic information

• Product Name: 3,3-BIS(METHYLTHIO)-2-(THEN-2-OYL)ACRYLONITRILE
• Synonyms: 3,3-BIS(METHYLTHIO)-2-(THEN-2-OYL)ACRYLONITRILE;3,3-di(methylthio)-2-(2-thienylcarbonyl)acrylonitrile
• CAS NO: 62455-60-1
• Molecular Formula: C10H9NOS3
• Molecular Weight: 255.38
• Mol File: 62455-60-1.mol
• Article Data: 1

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 3,3-BIS(METHYLTHIO)-2-(THEN-2-OYL)ACRYLONITRILE(CAS DataBase Reference)
• NIST Chemistry Reference: 3,3-BIS(METHYLTHIO)-2-(THEN-2-OYL)ACRYLONITRILE(62455-60-1)
• EPA Substance Registry System: 3,3-BIS(METHYLTHIO)-2-(THEN-2-OYL)ACRYLONITRILE(62455-60-1)

Safety Data

• Hazardous Substances Data: 62455-60-1(Hazardous Substances Data)

Upstream product

• 75-15-0 carbon disulfide 
• 33898-90-7 2-Thenoylacetonitrile 
• 74-88-4 methyl iodide 

Downstream Products

• 68364-50-1 2-amino-4-methylsulfanyl-6-thiophen-2-yl-pyrimidine-5-carbonitrile 

Relevant articles and documents

ALKYLIERUNGS- AND ARYLIERUNGSREAKTIONEN MIT GEMINALEN DITHIOLATEN

Acyl acetonitriles 1 react with carbon disulfide in the presence of sodium hydride to give disodium salts 2.Treatment of 2 with an alkylation reagent yields the open chain or cyclic acyl cyanketene S,S-acetals 3,4,8 and 10, respectively.Arylation to 11 is successful with 2,4-dinitro-chlorobenzene.Adding only one equivalent of methyl iodide to 2 and acidifying the reaction mixture lead to the monoalkylated compounds 7, whereas β-hydroxythioanilides 12 are available by reaction of 1 with phenyl isothiocyanate.A comparison of the ?-values shows that there exists the same type of the proton's chelation of the OH-group in 7 and 12.