6246-05-5

Basic information

• Product Name: 3-Aminomethyl-oxetane
• Synonyms: 3-Aminomethyl-oxetane;3-OxetaneMethanaMine;1-(Oxetan-3-yl)methanamine
• CAS NO: 6246-05-5
• Molecular Formula: C₄H₉NO
• Molecular Weight: 87.12036
• Mol File: 6246-05-5.mol
• Article Data: 3

Chemical Properties

• Boiling Point: 131℃
• Flash Point: 41℃
• Appearance: Colorless to pale yellow/Liquid
• Density: 1.004
• Vapor Pressure: 9.504mmHg at 25°C
• Refractive Index: 1.458
• Storage Temp.: ?20°C
• PKA: 9.65±0.29(Predicted)
• Sensitive: Air Sensitive
• CAS DataBase Reference: 3-Aminomethyl-oxetane(CAS DataBase Reference)
• NIST Chemistry Reference: 3-Aminomethyl-oxetane(6246-05-5)
• EPA Substance Registry System: 3-Aminomethyl-oxetane(6246-05-5)

Safety Data

• Hazard Codes: Xn
• Statements: 22-37/38-41
• Safety Statements: 26-39
• Hazardous Substances Data: 6246-05-5(Hazardous Substances Data)

Usage

General Description

3-Aminomethyl-oxetane is a chemical compound with the formula C4H9NO. It is also known as 3-amino-3-methyltetrahydrofuran and is classified as an oxetane derivative. 3-Aminomethyl-oxetane is used in the synthesis of various pharmaceuticals, agrochemicals, and materials due to its unique structural and chemical properties. It is commonly employed as a building block in the production of diverse heterocyclic compounds and is also used as a ligand in metalloorganic chemistry. Additionally, 3-Aminomethyl-oxetane has potential applications in the development of advanced materials, such as polymers and coatings, due to its reactivity and functional group versatility. However, its exact usage and properties may vary based on the specific applications and formulations.

InChI:InChI=1/C4H9NO/c5-1-4-2-6-3-4/h4H,1-3,5H2

Upstream product

• 1313739-08-0 3-nitromethyloxetane 
• 922500-95-6 3-(nitromethylene)oxetane 

Downstream Products

• 1595285-82-7 (E)-N-(4-((3-chloro-4-fluorophenyl)amino)thieno[2,3-d]pyrimidin-6-yl)-4-((oxetan-3-ylmethyl)amino)but-2-enamide 
• 1571134-05-8 C₂₆H₂₃F₃N₄O₃ 
• 1429241-42-8 1-(2,4-dichlorophenyl)-4-((oxetan-3-ylmethylamino)-methyl)-N-(piperidin-1-yl)-5-(5-((4-(trifluoromethyl)phenyl)-ethynyl)thiophene-2-yl)-1H-pyrazole-3-carboxamide 
• 1429241-65-5 5-(4-(isopropylsulfonyl)phenyl)-3-(3-(4-((oxetan-3-ylmethylamino)methyl)phenyl)isoxazol-5-yl)pyrazin-2-amine 

Relevant articles and documents

Novel bi-cyclic or tri-cyclic heterocyclic compound

The present invention provides novel bi-cyclic or tri-cyclic compound represented by formula (I) or pharmaceutical acceptable salt thereof, [wherein, ring A is an aromatic group which may be substituted, one of X1 and X2 is a carbon atom, and another is a nitrogen atom, X3 is a nitrogen atom or CR2, X4 is a nitrogen atom or CR3, X5 is a sulfur atom or -CH=CH-, Z1 is an oxygen atom, -C(R6)(R7)-, -NH-, -C(R6)(R7)-NH-, -NH-C(R6)(R7)-, -C(R6)(R7)-O-, -O-C(R6)(R7)- or a single bone, one of Z2 and Z3 is CH and another one is a nitrogen atom, or both are nitrogen atoms, the other symbols are same as those defined in the specification.]

METHODS FOR MAKING OXETAN-3-YLMETHANAMINES

This invention relates to methods for making oxetan-3-ylmethanamines having the formula (I) wherein R1? and R2? are as defined herein. The methods of the invention provide the compounds of formula (I) in high yields and under conditions amenable for large-scale commercial production.