62491-89-8 Usage
Uses
Used in Pharmaceutical Industry:
1-(2-chloroethyl)-3-pyridin-2-ylurea is used as a building block for the synthesis of pharmaceutical compounds. Its unique structure allows for the development of new drugs targeting infectious diseases, cancer, and other medical conditions. 1-(2-chloroethyl)-3-pyridin-2-ylurea's versatility in chemical reactions facilitates the creation of a diverse range of therapeutic agents.
Used in Agrochemical Industry:
1-(2-chloroethyl)-3-pyridin-2-ylurea is utilized as a starting material in the synthesis of agrochemicals, potentially serving as a pesticide or herbicide. Its chemical properties make it a promising candidate for the development of new products to protect crops and enhance agricultural productivity.
Used in Medicinal Chemistry:
In the field of medicinal chemistry, 1-(2-chloroethyl)-3-pyridin-2-ylurea is employed as a key intermediate for the development of novel drugs. Its structural features enable the design and synthesis of innovative therapeutic agents, contributing to the advancement of medical treatments for various health issues.
Check Digit Verification of cas no
The CAS Registry Mumber 62491-89-8 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 6,2,4,9 and 1 respectively; the second part has 2 digits, 8 and 9 respectively.
Calculate Digit Verification of CAS Registry Number 62491-89:
(7*6)+(6*2)+(5*4)+(4*9)+(3*1)+(2*8)+(1*9)=138
138 % 10 = 8
So 62491-89-8 is a valid CAS Registry Number.
62491-89-8Relevant academic research and scientific papers
Synthesis of nitrosourea derivatives of pyridine and piperidine as potential anticancer agents.
Crider,Lamey,Floss,Cassady,Bradner
, p. 848 - 851 (2007/10/02)
Nitrosourea derivatives 18-22 which utilize either a piperidine or pyridine ring as a carrier group were synthesized and evaluated for anticancer activity. N'-(1-Benzyl-4-piperidinyl)-N-(2-chloroethyl)-N-nitosourea hydrogen maleate (19) exhibited good activity against intracranial L1210 leukemia as well as the mouse ependymoblastoma brain tumor system. Compound 19 exhibited comparable activity in the Lewis lung carcinoma system to N,N'-bis(2-chloroethyl)-N-nitrosourea. Replacement of the N-benzyl group in both the 3-piperidinyl- and 4-piperidinylnitrosoureas resulted in less active compounds in all tumor systems tested. The 3-pyridylnitrosourea 22 was inactive in the L-1210 leukemia system.
