62496-54-2Relevant academic research and scientific papers
A Robust, Eco-Friendly Access to Secondary Thioamides through the Addition of Organolithium Reagents to Isothiocyanates in Cyclopentyl Methyl Ether (CPME)
Pace, Vittorio,Castoldi, Laura,Monticelli, Serena,Safranek, Sandra,Roller, Alexander,Langer, Thierry,Holzer, Wolfgang
supporting information, p. 18966 - 18970 (2016/01/26)
The nucleophilic addition of widely available and variously functionalized organolithium reagents to isothiocyanates represents a straightforward, high-yielding, one-pot method to access secondary thioamides. The simple reaction conditions required and the broad scope (>50 cases examples) makes it a robust and reliable method to access both simple and complex thioamides, including enantiopure ones. Noxious and unpleasant-smelling sulfurating agents, usually employed in the literature established methods, are avoided during the whole synthetic procedure thus, rendering the protocol highly attractive, also for sustainability aspects.
Chiral Polymethine Dyes, III. Synthesis and Spectroscopic Properties of an Unsymmetrical, Chiral Monomethine Cyanine Dye with Thiazolyl and Quinolinyl End Group
Reichardt, Christian,Budnik, Ulrich
, p. 927 - 930 (2007/10/02)
The synthesis of the unsymmetrical monomethine cyanine dye 6 in its monochiral (6a, b) and isochiral form (6c), first realized by Goetze in 1938, has been significantly improved and its spectroscopic properties have been studied.According to the synthetic
