62500-20-3Relevant academic research and scientific papers
Trifluoromethyl Vinyl Sulfide: A Building Block for the Synthesis of CF3S-Containing Isoxazolidines
Riesco-Domínguez, Alejandra,Van De Wiel, Jeroen,Hamlin, Trevor A.,Van Beek, Bas,Lindell, Stephen D.,Blanco-Ania, Daniel,Bickelhaupt, F. Matthias,Rutjes, Floris P. J. T.
, p. 1779 - 1789 (2018/02/23)
Trifluoromethyl vinyl sulfide, a potential building block for pharmaceutically and agrochemically relevant products, is prepared and used for the first time in high-pressure-mediated 1,3-dipolar cycloaddition reactions with nitrones to synthesize (trifluoromethyl)sulfanyl isoxazolidines.
Coupling of N -Nosylhydrazones with Nitrosoarenes: Transition-Metal-Free Approach to (Z)- N -Arylnitrones
Liu, Tingting,Liu, Zhaohong,Liu, Zhenhua,Hu, Donghua,Wang, Yeming
, p. 1728 - 1736 (2018/02/14)
An efficient and transition-metal-free protocol for the synthesis of (Z)- N -arylnitrones from the direct coupling of N -nosylhydrazones with nitrosoarenes under mild conditions is described. The protocol is compatible with a wide range of functional groups placed on both the reagents and provided the corresponding nitrones in good to excellent yields by simple recrystallization process. The use of these 1,3-dipoles for the synthesis of substituted indoles is elaborated for 2,3-diphenyl-1 H -indole.
Microwave mediated synthesis of spiro-(indoline-isoxazolidines): Mechanistic study and biological activity evaluation
Raunak,Kumar, Vineet,Mukherjee, Shubhasish,Poonam,Prasad, Ashok K.,Olsen, Carl E.,Sch?ffer, Susan J.C.,Sharma, Sunil K.,Watterson, Arthur C.,Errington, William,Parmar, Virinder S.
, p. 5687 - 5697 (2007/10/03)
Regioisomeric spiro-(indoline-isoxazolidines) have been synthesized in moderate yields by the cycloaddition reaction between ethyl (3-indolylidene) acetate and various substituted α,N-diphenylnitrones, using environmentally benign microwave technology. A
1,3-Dipolar cycloaddition reactions of nitrones to prop-1-ene-1,3-sultone
Tian, Li,Xu, Guo-Yan,Ye, Yong,Liu, Lun-Zu
, p. 1329 - 1334 (2007/10/03)
The reaction of prop-1-ene-1,3-sultone (1) with a variety of nitrones 2 afforded novel [3+2] cycloaddition products 3, 4, and 5 in good yield. Excellent regio- and stereoselectivity were achieved in the cycloaddition reaction with phenylnitrones.
?-? Molecular Complexes with Nitrones: PartIV - Substituent Effect in the Complexation of Aryl Nitrones with Tetracyanoethylene and 1,4-Benzoquinones
Nour El-Din, Ahmed M.
, p. 511 - 512 (2007/10/02)
Charge-transfer complexes of some substituted nitrones with tetracyanoethylene and 1,4-benzoquinones have been studied spectrophotometrically.The stoichiometry and apparent formation constants of the complexes have been determined.From the energies of the charge-transfer transitions, the ionization potentials of the donors have been obtained.
1,3-Dipolar Cycloaddition Reactions between some C-Aryl Nitrogen Oxides with Electron-deficient Dipolarophils
Nour-El-Din, Ahmed M.,Mourad, Aboul-Fetouh E.
, p. 908 - 914 (2007/10/02)
Both C-(2-methylphenyl)-N-phenyl and C-(3-methylphenyl)-N-phenyl nitrones (1a, b) reacted with N-phenylmaleinimide and fumaronitrile to give the normal primary cycloadducts.The reaction of the two nitrones (1a, b) with 4-phenyl-1,2,4-triazoline-3,5-dione and diacetylacetylene afforded rearrangement products.The unexpected 1,3,4-oxadiazolidin-2-ones were isolated from reaction with phenylisocyanate.In contrast, tetracyanoethylene forms charge-transfer complexes with both nitrones instead of cycloaddition products.The structural elucidation of the reaction products was made on the bases of the elemental analysis as well as i.r. and 1H-n.m.r. spectral data.
