625096-48-2Relevant academic research and scientific papers
Reductive desymmetrization of 2-alkyl-1,3-diketones catalyzed by optically active β-ketoiminato cobalt complexes
Ohtsuka, Yuhki,Koyasu, Kiichirou,Ikeno, Taketo,Yamada, Tohru
, p. 2543 - 2546 (2001)
(Equation presented) The reductive desymmetrization of acyclic 1,3-diketones was achieved for the first time by catalytic borohydride reduction in the presence of optically active β-ketoiminato cobalt(II) complex catalysts. In this reaction, various 2-sub
Enantioselective borohydride reduction catalyzed by optically active cobalt complexes
Yamada, Tohru,Nagata, Takushi,Sugi, Kiyoaki D.,Yorozu, Kiyotaka,Ikeno, Taketo,Ohtsuka, Yuhki,Miyazaki, Daichi,Mukaiyama, Teruaki
, p. 4485 - 4509 (2007/10/03)
The highly enantioselective borohydride reduction of aromatic ketones or imines to the corresponding alcohols was developed in the presence of a catalytic amount of an optically active cobalt(II) complex catalyst. This enantioselective reduction is carried out using a precisely premodified borohydride with alcohols such as tetrahydrofurfuryl alcohol, ethanol and methanol. High optical yields are obtained by choosing the appropriate alcohol as modifiers and a suitable β-ketoiminato ligand of the catalyst. The enantioselective borohydride reduction has been successfully applied to the preparation of optically active 1,3-diols, the stereoselective reduction of diacylferrocenes, and dynamic and/or kinetic resolution of 1,3-dicarbonyl compounds.
