625109-82-2

Upstream product

• 109-87-5 Dimethoxymethane 
• 625109-81-1 ethyl (2S,3R,5R,6Z,8S,9S,10S)-2-bromo-5,9-di-(tert-butyldimethylsiloxy)-11-(tert-butyldiphenylsiloxy)-3-hydroxy-2,8,10-trimethyl-6-undecenoate 
• 625109-95-7 (Z)-(3R,6S,7S,8S)-3,7-Bis-(tert-butyl-dimethyl-silanyloxy)-9-(tert-butyl-diphenyl-silanyloxy)-6,8-dimethyl-non-4-enoic acid phenyl ester 
• 625109-96-8 (Z)-(3R,6S,7S,8S)-3,7-Bis-(tert-butyl-dimethyl-silanyloxy)-9-(tert-butyl-diphenyl-silanyloxy)-6,8-dimethyl-non-4-en-1-ol 
• 625109-80-0 (3R,4Z,6S,7S,8S)-3,7-di-(tert-butyldimethylsiloxy)-9-(tert-butyldiphenylsiloxy)-6,8-dimethyl-4-nonenal 
• 625109-71-9 phenyl (3R,4Z,6S,7S,8S)-7-(tert-butyldimethylsiloxy)-9-(tert-butyldilphenylsiloxy)-3-hydroxy-6,8-dimethyl-4-nonenoate 

Downstream Products

• 625109-84-4 (2R,3R,5R,6Z,8S,9S,10S)-9-(tert-butyldimethylsiloxy)-11-(tert-butyldiphenylsiloxy)-2,8,10-trimethyl-3,5-methylenedioxy-6-undecenal 

Relevant academic research and scientific papers

Regulated-stereoselective construction of thirteen stereogenic centers necessary for the frame of (+)-discodermolide, based on iterative Lewis acid-promoted aldol reactions

The segments C1-C13 and C15-C 21 containing the 13 stereogenic centers required for the frame of (+)-discodermolide were synthesized in good to excellent enantio- and diastereoselectivities from a common racemic