625123-47-9

Upstream product

• 40216-83-9 L-4-hydroxyproline methyl ester hydrochloride 
• 18162-48-6 tert-butyldimethylsilyl chloride 
• 382137-65-7 methyl-(2S,4R)-N-[4-benzyloxy-5-methoxy-2-nitrobenzoyl]-4-hydroxypyrrolidine-2-carboxylate 
• 64154-78-5 4-benzyloxy-5-methoxy-2-nitrobenzoyl chloride 
• 60547-92-4 4-(benzyloxy)-5-methoxy-2-nitrobenzoic acid 
• 625123-46-8 methyl (2S,4R)-N-[4-benzyloxy-5-methoxy-2-nitrobenzoyl]-4-(t-butyldimethylsilyl)-oxypyrrolidine-2-carboxylate 

Downstream Products

• 625123-48-0 (2S,4R)-N-[4-benzyloxy-5-methoxy-2-nitrobenzoyl]-4-hydroxypyrrolidine-2-carboxaldehyde diethyl thioacetal 
• 642478-87-3 Methanesulfonic acid (3R,5S)-1-(4-benzyloxy-5-methoxy-2-nitro-benzoyl)-5-(bis-ethylsulfanyl-methyl)-pyrrolidin-3-yl ester 
• 642478-88-4 [(2S,4S)-4-Azido-2-(bis-ethylsulfanyl-methyl)-pyrrolidin-1-yl]-(4-benzyloxy-5-methoxy-2-nitro-phenyl)-methanone 
• 642478-89-5 [(2S,4S)-4-Amino-2-(bis-ethylsulfanyl-methyl)-pyrrolidin-1-yl]-(4-benzyloxy-5-methoxy-2-nitro-phenyl)-methanone 
• 757189-96-1 (2S)-N-{4-[(2S)-N-(4-benzyloxy-5-methoxy-2-nitrobenzoyl)-pyrrolidine-2-carboxaldehyde diethyl thioacetal-4-(carboxamidomethylidene)-N-propyl]oxy-5-methoxy-2-nitrobenzoyl}pyrrolidine-2-carboxaldehyde diethyl thioacetal 
• 757190-00-4 (2S)-N-{4-[(2S)-N-(4-benzyloxy-5-methoxy-2-aminobenzoyl)-pyrrolidine-2-carboxaldehyde diethyl thioacetal-4-(carboxamidomethylidene)-N-propyl]oxy-5-methoxy-2-aminobenzoyl}pyrrolidine-2-carboxaldehyde diethyl thioacetal 
• 757189-95-0 (2S)-N-{4-[(2S)-N-[4-benzyloxy-5-methoxy-2-nitrobenzoyl]-pyrrolidine-2-carboxaldehyde diethyl thioacetal-4-(carboxamidomethylidene)-N-ethyl]oxy-5-methoxy-2-nitrobenzoyl}pyrrolidine-2-carboxaldehyde diethyl thioacetal 
• 757189-99-4 (2S)-N-{4-[(2S)-N-(4-benzyloxy-5-methoxy-2-aminobenzoyl)-pyrrolidine-2-carboxaldehyde diethyl thioacetal-4-(carboxamidomethylidene)-N-ethyl]oxy-5-methoxy-2-aminobenzoyl}pyrrolidine-2-carboxaldehyde diethyl thioacetal 
• 757190-10-6 methyl (2S)-N-{4-[(2S)-N-(4-benzyloxy-5-methoxy-2-nitrobenzoyl)-pyrrolidine-2-carboxaldehyde diethyl thioacetal-4-(carboxamidomethylidene)-N-propyl]oxy-5-methoxy-2-nitrobenzoyl}pyrrolidine-2-carboxylate 
• 757190-09-3 methyl (2S)-N-{4-[(2S)-N-(4-benzyloxy-5-methoxy-2-nitrobenzoyl)-pyrrolidine-2-carboxaldehyde diethyl thioacetal-4-(carboxamidomethylidene)-N-ethyl]oxy-5-methoxy-2-nitrobenzoyl}pyrrolidine-2-carboxylate 
• 757189-98-3 (2S)-N-{4-[(2S)-N-(4,5-dimethoxy-2-nitrobenzoyl)-pyrrolidine-2-carboxaldehyde diethyl thioacetal-4-(carboxamidomethylidene)-N-propyl]oxy-5-methoxy-2-nitrobenzoyl}pyrrolidine-2-carboxaldehyde diethyl thioacetal 
• 757190-12-8 7-methoxy-8-{3-[(2S)-N-(4-benzyloxy-5-methoxy-2-aminobenzoyl)pyrrolidine-2-carboxaldehyde diethyl thioacetal-4-(carboxamidomethylidene)-propyl]oxy}-(11aS)-1,2,3,10,11,11a-hexahydro-5H-pyrrolo[2,1-c][1,4]-benzodiazepin-5,11-dione 
• 757190-02-6 (2S)-N-{4-[(2S)-N-(4,5-dimethoxy-2-aminobenzoyl)-pyrrolidine-2-carboxaldehyde diethyl thioacetal-4-(carboxamidomethylidene)-N-propyl]oxy-5-methoxy-2-aminobenzoyl}pyrrolidine-2-carboxaldehyde diethyl thioacetal 
• 757189-97-2 (2S)-N-{4-[(2S)-N-(4,5-dimethoxy-2-nitrobenzoyl)-pyrrolidine-2-carboxaldehyde diethyl thioacetal-4-(carboxamidomethylidene)-N-ethyl]oxy-5-methoxy-2-nitrobenzoyl}pyrrolidine-2-carboxaldehyde diethyl thioacetal 

Relevant academic research and scientific papers

Synthesis and DNA binding affinity of novel A-C8/C-C2-exo unsaturated alkoxyamido-linked pyrrolo[2,1-c][1,4]benzodiazepine dimers.

The synthesis of novel A-C8/C-C2-exo unsaturated alkoxyamido-linked pyrrolo[2,1-c][1,4]benzodiazepine dimers is reported and these dimers show significant DNA binding affinity and they also exhibit moderate anticancer activity.

Synthesis and DNA-binding affinity of A-C8/C-C2 alkoxyamido-linked pyrrolo[2,1-c][1,4]benzodiazepine dimers

The synthesis of new A-C8/C-C2 alkoxyamido-linked pyrrolo[2,1-c][1,4]- benzodiazepine dimers have been described in this report. These dimers exhibit significant DNA-binding ability with moderate anticancer activity.

Synthesis of novel C2 and C2-C8 linked pyrrolo[2,1-c][1,4]benzodiazepine-naphthalimide hybrids as DNA-binding agents

Synthesis of C2 and C2-C8 linked pyrrolobenzodiazepine-naphthalimide hybrids have been prepared that exhibit significant DNA-binding affinity and cytotoxicity.