625127-09-5

Basic information

• Product Name: 2(1H)-ISOQUINOLINECARBOXYLIC ACID, 7-BROMO-3,4-DIHYDRO-, PHENYLMETHYL ESTER
• Synonyms: 2(1H)-ISOQUINOLINECARBOXYLIC ACID, 7-BROMO-3,4-DIHYDRO-, PHENYLMETHYL ESTER;Benzyl 7-broMo-3,4-dihydroisoquinoline-2(1H)-carboxylate
• CAS NO: 625127-09-5
• Molecular Formula: C₁₇H₁₆BrNO₂
• Molecular Weight: 346.23
• Mol File: 625127-09-5.mol

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 2(1H)-ISOQUINOLINECARBOXYLIC ACID, 7-BROMO-3,4-DIHYDRO-, PHENYLMETHYL ESTER(CAS DataBase Reference)
• NIST Chemistry Reference: 2(1H)-ISOQUINOLINECARBOXYLIC ACID, 7-BROMO-3,4-DIHYDRO-, PHENYLMETHYL ESTER(625127-09-5)
• EPA Substance Registry System: 2(1H)-ISOQUINOLINECARBOXYLIC ACID, 7-BROMO-3,4-DIHYDRO-, PHENYLMETHYL ESTER(625127-09-5)

Safety Data

• Hazardous Substances Data: 625127-09-5(Hazardous Substances Data)

Usage

Properties

Chemical compound
Belongs to the class of isoquinolines
Also known as brake fluid dye
Used as an intermediate in the pharmaceutical industry
Has potential use in chemical and biological research

Applications

Synthesis of various medicines, research and development for new drugs and treatments

Additional notes

Further research and testing needed to determine potential uses and safety profiles.

Upstream product

• 17680-55-6 7-bromo-1,2,3,4-tetrahydroisoquinoline 
• 501-53-1 benzyl chloroformate 
• 50-00-0 formaldehyd 
• 191170-76-0 benzyl N-[2-(4-bromophenyl)ethyl]carbamate 

Downstream Products

• 625127-14-2 C₂₂H₂₀N₂O₂ 
• 17680-55-6 7-bromo-1,2,3,4-tetrahydroisoquinoline 
• 220247-62-1 7-bromo-N-triphenylmethyl-1,2,3,4-tetrahydroisoquinoline 

Relevant articles and documents

NOVEL MORPHOLINYL AMINE COMPOUNDS FOR THE TREATMENT OF AUTOIMMUNE DISEASE

The present invention relates to compounds of formula (I), wherein R1, R2 and R3 are as described herein, and their pharmaceutically acceptable salt, enantiomer or diastereomer thereof, and compositions including the compounds and methods of using the compounds.

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Substituted norbenzomorphans are known to display high affinity and selectivity for the two sigma receptor (σR) subtypes. In order to study the effects of simplifying the structures of these compounds, a scaffold hopping strategy was used to design severa

THIENOPYRIDINE CARBOXAMIDES AS UBIQUITIN-SPECIFIC PROTEASE INHIBITORS

The disclosure relates to inhibitors of USP28 and/or USP25 useful in the treatment of cancers, inflammation, autoimmune diseases, and infectious diseases, having the Formula (I), where R1, R2, R3, R4, R5, R5', R6, R7, X, m, and n are described herein.

SIGMA RECEPTOR BINDERS

Provided herein, inter alia, are compounds and methods of treating diseases including cancer, neurological disease, alcohol withdrawal, depression and anxiety, and neuropathic pain.

TETRAHYDROPYRANYL CYCLOPENTYL TETRAHYDROISOQUINOLINE MODULATORS OF CHEMOKINE RECEPTOR ACTIVITY

The present invention is directed to compounds of the formula I: I(wherein R1, R2, R3, R4, R5, R6, R7, R8, R9, R10, X, n and the dashed line are defined herein) which are useful as modulators of chemokine receptor activity. In particular, these compounds are useful as modulators of the chemokine receptor CCR-2.