62516-59-0

Upstream product

• 104-87-0 4-methyl-benzaldehyde 
• 292638-85-8 acrylic acid methyl ester 
• 1752-88-1 tetrahydro-3H-pyrazol-3-one hydrochloride 
• 17822-51-4 1-benzylidene-3-oxo-1-pyrazolidinium-2-ide 

Downstream Products

• 1173920-40-5 dimethyl 8-(tert-butylimino)-1-oxo-5-(4-tolyl)-2,3,5,8-tetrahydro-1H-pyrazolo[1,2-a]pyridazine-6,7-dicarboxylate 
• 1198298-03-1 C₁₇H₁₆N₂O 
• 1245187-54-5 C₁₇H₁₈N₂O 
• 1258237-32-9 tert-butyl 1-(4-methylphenyl)-5-oxo-2-(trifluoromethyl)tetrahydro-1H,5H-pyrazolo[1,2-a]pyrazole-2-carboxylate 
• 1321111-99-2 (E)-ethyl 2-(7-oxo-3-(p-tolyl)tetrahydropyrazolo[1,2-a]pyrazol-1(5H)-ylidene)propanoate 
• 1375101-62-4 (E)-ethyl 2-(7-oxo-3-p-tolyltetrahydropyrazolo[1,2-a]pyrazol-1(5H)-ylidene)acetate 
• 1415506-31-8 5-(4-methylphenyl)-7-phenyl-2,3-dihydropyrazolo[1,2-a]pyrazol-1(5H)-one 
• 1417612-25-9 methyl 6-(tert-butyldimethylsilyl)oxy-3-oxo-8-(p-tolyl)-2,3,7,8-tetrahydro-1Hpyrazolo[1,2-a]pyridazine-5-carboxylate 
• 1446877-34-4 (1'S,2'R,3'R)-1-tert-butyl 3'-ethyl 2,5'-dioxo-1'-(p-tolyl)-3',5',6',7'-tetrahydro-1'H-spiro[indoline-3,2'-pyrazolo[1,2-a]pyrazole]-1,3'-dicarboxylate 
• 1450841-18-5 (R)-ethyl 5-oxo-1-(p-tolyl)-1,5,6,7-tetrahydropyrazolo[1,2-a]pyrazole-2-carboxylate 

Relevant academic research and scientific papers

Br?nsted Acid-Catalyzed (4 + 3) Cyclization of N, N′-Cyclic Azomethine Imines with Isatoic Anhydrides

A Br?nsted acid-catalyzed (4 + 3) cyclization of N,N′-cyclic azomethine imines with isatoic anhydrides has been discovered, which constructs seven-membered nitrogenous heterocyclic frameworks with overall high yields (up to 98% yield). This reaction repre

Enantioselective copper-catalyzed [3+3] cycloaddition of azomethine ylides with azomethine imines

The more dipoles, the merrier: An asymmetric [3+3] cycloaddition of azomethine ylides derived from imines 1 with azomethine imines 2 in the presence of a chiral ferrocenylphosphine-copper catalyst afforded highly functionalized heterocyclic products 3 in high yield with excellent enantio- and diastereoselectivity (see scheme; DBU=1,8-diazabicyclo[5.4.0]undec-7-ene). The 1,3-dipolar reaction partners can be readily prepared from aldehydes. Copyright

Dirhodium(ii)-catalyzed formal [3+2+1]-annulation of azomethine imines with two molecules of a diazo ketone

A highly diastereoselective formal [3+2+1]-cycloaddition reaction that produces multi-functionalized bicyclic pyrazolidinone derivatives is achieved in moderate to high yield by Rh2(4S-MPPIM)4-catalyzed reaction of azomethine imines with two molecules of a diazo ketone. The Royal Society of Chemistry 2013.

Copper(I) acetate-catalyzed cycloaddition between azomethine imines and propiolates under additive-free conditions

Because propiolates easily undergo base-catalyzed self-Michael addition, most popular catalytic systems in CuAAC cannot be used in the cycloaddition between azomethine imines and propiolates, because such reactions usually require the use of tertiary amin