62524-16-7Relevant academic research and scientific papers
Synthesis of amides from acid chlorides and amines in the bio-based solvent Cyrene
Bousfield, Thomas W.,Pearce, Katharine P. R.,Nyamini, Simbarashe B.,Angelis-Dimakis, Athanasios,Camp, Jason E.
supporting information, p. 3675 - 3681 (2019/07/09)
Cyrene as a bio-alternative dipolar aprotic solvent: a waste minimizing and molar efficient protocol for the synthesis of amides from acid chlorides and primary amines in the bio-available solvent Cyrene is disclosed. This protocol removed the use of toxic solvents, such as dimethylformamide and dichloromethane. A simple aqueous work-up procedure for the removal of the high boiling solvent Cyrene resulted in up to a 55-fold increase in molar efficiency (Mol E.%) versus standard operating procedures. In order to rapidly compare the molar efficiency of this process against other methodologies an Excel based Mol. E% calculator was developed that automates many of the calculations. An investigation into the hydration of Cyrene found that it readily hydrates to form a geminal diol in the presence of water and that this process is exothermic.
A STUDY OF PHOTOCYCLIZATION OF O-ALKYL N-(3-CHLORO-2-BENZOTHIENOCARBONYL)MONOTHIOCARBAMATES
Kutschy, Peter,Imrich, Jan,Bernat, Juraj,Kristian, Pavol,Fedorikova, Iveta
, p. 2002 - 2012 (2007/10/02)
The O-alkyl N-(3-chloro-2-benzothienocarbonyl)monothiocarbamates prepared by the reaction of 2-isothiocyanatocarbonyl-3-chlorobenzothiophene with methanol, ethanol, 1-propanol, and 2-propanol are cyclized on irradiation with light of the wavelength
Synthesis of Condensed Carbostyrils
Jayachandran, T.,Paramasivam, R.,Ramakrishnan, V. T.
, p. 89 - 91 (2007/10/02)
3-Chloro-1-benzothiophene-2-carboxanilides (1) on treatment with aluminium chloride or under irradiation give benzothienoquinoline-6(5H)-ones (2).
