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625367-14-8

C13H11F3N2O2 is a chemical with a specific purpose. Lookchem provides you with multiple data and supplier information of this chemical.

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  • 625367-14-8 Structure

  • Basic information

    1. Product Name: C13H11F3N2O2
    2. Synonyms:
    3. CAS NO:625367-14-8
    4. Molecular Formula:
    5. Molecular Weight: 284.238
    6. EINECS: N/A
    7. Product Categories: N/A
    8. Mol File: 625367-14-8.mol

  • Chemical Properties

    1. Melting Point: N/A
    2. Boiling Point: N/A
    3. Flash Point: N/A
    4. Appearance: N/A
    5. Density: N/A
    6. Refractive Index: N/A
    7. Storage Temp.: N/A
    8. Solubility: N/A
    9. CAS DataBase Reference: C13H11F3N2O2(CAS DataBase Reference)
    10. NIST Chemistry Reference: C13H11F3N2O2(625367-14-8)
    11. EPA Substance Registry System: C13H11F3N2O2(625367-14-8)

  • Safety Data

    1. Hazard Codes: N/A
    2. Statements: N/A
    3. Safety Statements: N/A
    4. WGK Germany:
    5. RTECS:
    6. HazardClass: N/A
    7. PackingGroup: N/A
    8. Hazardous Substances Data: 625367-14-8(Hazardous Substances Data)

625367-14-8 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 625367-14-8 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 6,2,5,3,6 and 7 respectively; the second part has 2 digits, 1 and 4 respectively.
Calculate Digit Verification of CAS Registry Number 625367-14:
(8*6)+(7*2)+(6*5)+(5*3)+(4*6)+(3*7)+(2*1)+(1*4)=158
158 % 10 = 8
So 625367-14-8 is a valid CAS Registry Number.

625367-14-8Relevant articles and documents

Quinoline-3-carboxamide containing sulfones as liver X receptor (LXR) agonists with binding selectivity for LXRβ and low blood-brain penetration

Hu, Baihua,Bernotas, Ron,Unwalla, Rayomand,Collini, Michael,Quinet, Elaine,Feingold, Irene,Goos-Nilsson, Annika,Wilhelmsson, Anna,Nambi, Ponnal,Evans, Mark,Wrobel, Jay

scheme or table, p. 689 - 693 (2010/06/14)

A series of quinoline-3-carboxamide containing sulfones was prepared and found to have good binding affinity for LXRβ and moderate binding selectivity over LXRα. The 8-Cl quinoline analog 33 with a high TPSA score, displayed 34-fold binding selectivity for LXRβ over LXRα (LXRβ IC50 = 16 nM), good activity for inducing ABCA1 gene expression in a THP macrophage cell line, desired weak potency in the LXRα Gal4 functional assay, and low blood-brain barrier penetration in rat.

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