6255-72-7Relevant academic research and scientific papers
Tight binding ligand approach to oligosaccharide-grafted protein
Totani, Kiichiro,Matsuo, Ichiro,Ito, Yukishige
, p. 2285 - 2289 (2007/10/03)
A novel type of artificial glycoprotein was developed, by using dihydrofolate reductase (DHFR) and methotrexate (MTX) as a protein-ligand pair. Various oligosaccharides linked to MTX were shown to bind tightly with DHFR and afforded oligosaccharide-grafted protein, which could be isolated easily by lectin beads.
Synthesis of N4-(2-acetamido-2-deoxy-β-D-glucopyranosyl)-L-asparagine analogues. Complete NMR assignments of chloroacetamide, bromoacetamide and glycinamide analogues
Malik, Jayshri J.,Risley, John M.
, p. 98 - 100 (2007/10/03)
N4-(2-Acetamido-2-deoxy-β-D-glucopyranosyl)-L-asparagine is the principle linkage in the structure of N-linked glycoproteins. Complete assignments of the 1H and 13C NMR spectra for three analogues of the naturally-occurring N-glycosylic structure were made for N-(2-acetamido-2-deoxy-β-D-glucopyranosyl)chloroacetamide, N-(2-acetamido-2-deoxy-β-D-glucopyranosyl)bromoacetamide and N1-(2-acetamido-2-deoxy-β-D-glucopyranosyl)glycinamide. The methylene groups adjacent to the N-glycosylic bond are AB spin systems. Copyright
N-glycyl-β-glycopyranosylamines, derivatives of mono- and disaccharides, and their use for the preparation of carboxylic acid glycoconjugates
Likhosherstov,Novikova,Zheltova,Shibaev
, p. 1454 - 1459 (2007/10/03)
A convenient preparative procedure was developed for the synthesis of N-glycyl-β-glycopyranosylamines, derivatives of monosaccharides (D-galactose, D-mannose, L-fucose, and N-acetyl-D-glucosamine) and disaccharides (lactose, melibiose, cellobiose, and mal
