625822-10-8

Basic information

• Product Name: (2R,3S,4S,5R)-tert-butyl-[5-(2,6-dichlorobenzyloxymethyl)-4-(1H-imidazole-1-carbothioate)-3-methyltetrahydrofuran-2-yl-methoxy]dimethylsilane
• Synonyms: (2R,3S,4S,5R)-tert-butyl-[5-(2,6-dichlorobenzyloxymethyl)-4-(1H-imidazole-1-carbothioate)-3-methyltetrahydrofuran-2-yl-methoxy]dimethylsilane
• CAS NO: 625822-10-8
• Molecular Weight: 545.602
• Mol File: 625822-10-8.mol

Chemical Properties

• CAS DataBase Reference: (2R,3S,4S,5R)-tert-butyl-[5-(2,6-dichlorobenzyloxymethyl)-4-(1H-imidazole-1-carbothioate)-3-methyltetrahydrofuran-2-yl-methoxy]dimethylsilane(CAS DataBase Reference)
• NIST Chemistry Reference: (2R,3S,4S,5R)-tert-butyl-[5-(2,6-dichlorobenzyloxymethyl)-4-(1H-imidazole-1-carbothioate)-3-methyltetrahydrofuran-2-yl-methoxy]dimethylsilane(625822-10-8)
• EPA Substance Registry System: (2R,3S,4S,5R)-tert-butyl-[5-(2,6-dichlorobenzyloxymethyl)-4-(1H-imidazole-1-carbothioate)-3-methyltetrahydrofuran-2-yl-methoxy]dimethylsilane(625822-10-8)

Safety Data

• Hazardous Substances Data: 625822-10-8(Hazardous Substances Data)

Upstream product

• 6160-65-2 1,1'-Thiocarbonyldiimidazole 
• 625822-04-0 (2R,3R,4S,5R)-5-(tert-butyldimethylsilanyloxymethyl)-2-(2,6-dichlorobenzyloxymethyl)-4-methyltetrahydrofuran-2-ol 
• 88424-95-7 2,3-O-isopropylidene-1-C-<(1S)-1-methylprop-2-enyl>-D-erythro-glycerol 
• 625821-86-5 (S)-1-((R)-2,2-Dimethyl-[1,3]dioxolan-4-yl)-2-methyl-but-3-en-1-one 
• 625821-91-2 (2R,3S,4S)-3-(4-Methoxy-benzyloxy)-4-methyl-hex-5-ene-1,2-diol 
• 625822-13-1 (R)-4-[(1S,2S)-1-(4-Methoxy-benzyloxy)-2-methyl-but-3-enyl]-2,2-dimethyl-[1,3]dioxolane 
• 625822-02-8 (2R,3R,4S,5R)-[5-(2,6-dichlorobenzyloxymethyl)-4-(4-methoxybenzyloxy)-3-methyltetrahydrofuran-2-yl]methanol 
• 625822-01-7 (2R,3S,4R,5R)-2-(2,6-dichlorobenzyloxymethyl)-5-iodomethyl-3-(4-methoxybenzyloxy)-4-methyltetrahydrofuran 
• 625822-03-9 (2R,3R,4S,5R)-tert-butyl-[5-(2,6-dichlorobenzyloxymethyl)-4-(4-methoxyphenoxymethyl)-3-methyltetrahydrofuran-2-ylmethoxy]dimethylsilane 
• 625821-98-9 (3S,4S,5R)-5,6-bis-(2,6-dichlorobenzyloxy)-4-(4-methoxybenzyloxy)-3-methylhex-1-ene 
• 18162-48-6 tert-butyldimethylsilyl chloride 

Downstream Products

• 930795-42-9 acetic acid 1-[1-(2-cyano-ethyl)-4-(2,2-dimethyl-[1,3]dioxolan-4-yl)-2-formyl-3-methyl-cyclohex-3-enyl]-5-[3-methyl-5-(3-triisopropylsilanyloxy-propyl)-tetrahydro-furan-2-yl]-hex-4-enyl ester 
• 930795-41-8 (4E)-1-((1R,2S)-1-(2-cyanoethyl)-2-(hydroxymethyl)-3-methyl-4-((R)-2,2-dimethyl-1,3-dioxolan-4-yl)cyclohex-3-enyl)-5-((2R,3R,5R)-5-(3-triisopropylsilanyloxypropyl)-3-methyltetrahydrofuran-2-yl)hex-4-enyl acetate 
• 930795-43-0 (4E)-1-((1R,2S)-1-(2-cyanoethyl)-2-ethynyl-3-methyl-4-((R)-2,2-dimethyl-1,3-dioxolan-4-yl)cyclohex-3-enyl)-5-((2R,3R,5R)-5-(3-triisopropylsilanyloxypropyl)-3-methyltetrahydrofuran-2-yl)hex-4-enyl acetate 
• 930795-40-7 (4E)-1-((1R,2S)-1-(2-cyanoethyl)-2-(triethylsilanyloxymethyl)-3-methyl-4-((R)-2,2-dimethyl-1,3-dioxolan-4-yl)cyclohex-3-enyl)-5-((2R,3R,5R)-5-(3-triisopropylsilanyloxypropyl)-3-methyltetrahydrofuran-2-yl)hex-4-enyl acetate 
• 625822-06-2 (2R,3R,5R)-5-(2,6-dichlorobenzyloxymethyl)-3-methyltetrahydrofuran-2-carbaldehyde 
• 625822-11-9 (2R,3R,5S)-5-(2,6-dichlorobenzyloxymethyl)-3-methyltetrahydrofuran-2-ylmethanol 
• 625822-07-3 (2R,3R,5R)-5-(2,6-dichlorobenzyloxymethyl)-2-ethynyl-3-methyltetrahydrofuran 
• 625822-08-4 (2R,3R,5S)-5-(2,6-dichlorobenzyloxymethyl)-2-[(E)-2-iodo-1-methylvinyl]-3-methyltetrahydrofuran 
• 625822-05-1 (2R,3R,4S,5R)-tert-butyl-[5-(2,6-dichlorobenzyloxymethyl)-3-methyltetrahydrofuran-2-ylmethoxy]dimethylsilane 

Relevant articles and documents

Studies on the synthesis of (-)-gymnodimine. Subunit synthesis and coupling

Two principal subunits of the marine algal toxin (-)-gymnodimine were synthesized. A trisubstituted tetrahydrofuran representing C10-C18 of the toxin was prepared via a highly stereoselective iodine-mediated cyclization of an acyclic alkene bearing a bis-

Studies on the Synthesis of Gymnodimine. Stereocontrolled Construction of the Tetrahydrofuran Subunit

(Equation presented) A bis-(2,6-dichlorobenzyl) ether is shown to undergo efficient and highly stereoselective intramolecular iodoetherification to yield a cis-2,5-disubstituted tetrahydrofuran, thus providing a powerful illustration of a stereodirecting