62590-02-7Relevant academic research and scientific papers
Concise synthesis of semicarbazides and formylhydrazines via direct addition reaction between aromatic azoarenes and N-substituted formamides
Liu, Defu,Mao, Jincheng,Rong, Guangwei,Yan, Hong,Zheng, Yang,Chen, Jie
, p. 19301 - 19305 (2015)
The addition reactions between aromatic azoarenes and N-substituted formamides are described. This direct and practical method provides a novel approach for the synthesis of formylhydrazines and semicarbazides in the presence of NaI/DTBP and imidazole/DCP catalytic systems, respectively. It can be seen that C-H or C-N from N-substituted formamides could be cleaved selectively under such transition-metal-free conditions. This is the first successful example of direct addition of N-substituted formamides to a NN bond.
