626-69-7 Usage
Uses
H-Ser(SO3H)-OH is used in methods and combinations for modulating tolerance to opiates, opioids or opioid analgesics and treating acute and chronic pain.
Definition
ChEBI: A non-proteinogenic L-alpha-amino acid that is the O-sulfo derivative of L-serine.
Check Digit Verification of cas no
The CAS Registry Mumber 626-69-7 includes 6 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 3 digits, 6,2 and 6 respectively; the second part has 2 digits, 6 and 9 respectively.
Calculate Digit Verification of CAS Registry Number 626-69:
(5*6)+(4*2)+(3*6)+(2*6)+(1*9)=77
77 % 10 = 7
So 626-69-7 is a valid CAS Registry Number.
InChI:InChI=1/C3H7NO6S/c4-2(3(5)6)1-10-11(7,8)9/h2H,1,4H2,(H,5,6)(H,7,8,9)/t2-/m0/s1
626-69-7Relevant articles and documents
Mechanism and Stereochemistry of the Activation of (2S)- and (2R)-Serine O-Sulfate as Suicide Inhibitors for Escherichia coli Glutamic Acid Decarboxylase
Rose, Janet E.,Leeson, Paul D.,Gani, David
, p. 3089 - 3094 (2007/10/02)
E. coli glutamic acid decarboxylase is inactivated by both enantiomers of the suicide inhibitor serine O-sulfate; inactivation by the (2S)-enantiomer involves Cα-H bond cleavage while inactivation by the (2R)-isomer involves Cα-decarboxylation.Both processes occur on the 4'-Re-face of the coenzyme, the opposite face to that utilised in physiological decarboxylation.
