626-69-7 Usage
Uses
Used in Pharmaceutical Industry:
H-SER(SO3H)-OH is used as a therapeutic agent for modulating tolerance to opiates, opioids, or opioid analgesics. Its unique properties allow it to potentially reduce the development of tolerance and dependence associated with the long-term use of these drugs, thereby improving their efficacy and safety in pain management.
H-SER(SO3H)-OH is also used as a treatment for acute and chronic pain. Its ability to modulate tolerance to opiates and opioids may provide a more effective and sustainable approach to pain relief, particularly for patients suffering from chronic pain conditions.
Check Digit Verification of cas no
The CAS Registry Mumber 626-69-7 includes 6 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 3 digits, 6,2 and 6 respectively; the second part has 2 digits, 6 and 9 respectively.
Calculate Digit Verification of CAS Registry Number 626-69:
(5*6)+(4*2)+(3*6)+(2*6)+(1*9)=77
77 % 10 = 7
So 626-69-7 is a valid CAS Registry Number.
InChI:InChI=1/C3H7NO6S/c4-2(3(5)6)1-10-11(7,8)9/h2H,1,4H2,(H,5,6)(H,7,8,9)/t2-/m0/s1
626-69-7Relevant academic research and scientific papers
Mechanism and Stereochemistry of the Activation of (2S)- and (2R)-Serine O-Sulfate as Suicide Inhibitors for Escherichia coli Glutamic Acid Decarboxylase
Rose, Janet E.,Leeson, Paul D.,Gani, David
, p. 3089 - 3094 (2007/10/02)
E. coli glutamic acid decarboxylase is inactivated by both enantiomers of the suicide inhibitor serine O-sulfate; inactivation by the (2S)-enantiomer involves Cα-H bond cleavage while inactivation by the (2R)-isomer involves Cα-decarboxylation.Both processes occur on the 4'-Re-face of the coenzyme, the opposite face to that utilised in physiological decarboxylation.
