62618-09-1Relevant articles and documents
DERIVATIVES OF BETA-ADRENERGIC ANTAGONISTS
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, (2008/06/13)
Molecular structures of β-adrenergic antagonists are modified to produce biologically active compounds. The β-antagonists are modified to form molecules of the general structure: STR1 wherein R is most generally R"--OCH 2--, and in some instances is R"--, and R"=an aryl or substituted aryl moiety; R'=--H,--CH 3, or a short chain alkyl moiety; and Y=--OH, or more usually,--OAX or--NHAX, where A=an alkyl, aryl, or aralkyl moiety, and X=a terminal grouping, such as--CH 3,--CF 3 or--(CH 2) n COOH; or AX may be a carrier moiety consisting of a defined peptide or protein. "