626225-56-7

Upstream product

• 1867-38-5 4-chlorobenzylidenemalonodinitrile 
• 91-68-9 3-diethylaminophenol 
• 104-88-1 4-chlorobenzaldehyde 
• 109-77-3 malononitrile 
• 1269625-07-1 2-benzylideneamino-4-(4-chlorophenyl)-7-(diethylamino)-4H-chromene-3-carbonitrile 

Downstream Products

• 1269625-05-9 2-diacetylamino-4-(4-chlorophenyl)-7-(diethylamino)-4H-chromene-3-carbonitrile 
• 1269625-06-0 5-(4-chlorophenyl)-8-(diethylamino)-2-methyl-3,4-dihydro-5H-chromeno-[2,3-d]-pyrimidin-4-one 
• 1269625-08-2 4-(4-chlorophenyl)-7-(diethylamino)-2-ethoxymethyleneamino-4H-chromene-3-carbonitrile 
• 1269625-09-3 5-(4-chlorophenyl)-N,N-diethyl-2-methyl-4-oxo-4,5-dihydro-3H-chromeno[2,3-d]-pyrimidin-8-aminium acetate 
• 1269625-07-1 2-benzylideneamino-4-(4-chlorophenyl)-7-(diethylamino)-4H-chromene-3-carbonitrile 
• 1269625-13-9 4-amino-5-(4-chlorophenyl)-8-(diethylamino)-5H-chromeno[2,3-d]pyrimidine 
• 1300638-87-2 12-(4-chlorophenyl)-9-diethylamino-12H-chromeno[3,2-e][1,2,4]triazolo[1,5-c]pyrimidine 
• 1300638-89-4 12-(4-chlorophenyl)-2-cyanomethyl-9-diethylamino-12H-chromeno[3,2-e][1,2,4]triazolo[1,5-c]pyrimidine 
• 1300638-92-9 ethyl 12-(4-chlorophenyl)-9-diethylamino-12H-chromeno[3,2-e][1,2,4]triazolo[1,5-c]pyrimidine-2-carboxylate 
• 1300639-02-4 3-benzylideneamino-5-(4-chlorophenyl)-8-diethylamino-4-imino-3,4-dihydro-5H-chromeno[2,3-d]pyrimidine 
• 1300638-94-1 3-ethoxycarbonyl-12-(4-chlorophenyl)-8-diethylamino-4-imino-3,4-dihydro-5H-chromeno[2,3-d]pyrimidine 

Relevant academic research and scientific papers

Convenient synthesis of 2-Amino-4H-chromenes from photochemically generated o-quinone methides and malononitrile

2-Amino-4H-chromenes were synthesized in moderate to good yields by the reaction of o-quinone methides photochemically generated from o-(dimethylaminomethyl)phenols with malononitrile. This method was applicable to the synthesis of fluorinated chromenes that were difficult to obtain by other methods. In addition, o-(hydroxymethyl)phenols could be used for the reaction in the presence of tertiary amine bases.

Synthesis, structure-activity relationship (SAR) studies on some 4-aryl-4H-chromenes and relationship between lipophilicity and antitumor activity

Some 4-aryl-4H-chromenes 3a-h, 5a-g, 7a-g and 9a-g were obtained by reaction of 3-substituted phenol 1,4,6 and 8 with α-cyanocinnamonitrile derivatives 2. We explored the structure activity relationship (SAR) of 4-aryl-4H-chromenes with modification at th

Synthesis of 4H-chromene, coumarin, 12H-chromeno[2,3-d]pyrimidine derivatives and some of their antimicrobial and cytotoxicity activities

Condensation of 3-N,N-diethylaminophenol (1) with α- cyanocinnamonitriles (2a-c) and ethyl α-cyanocinnamates (2d-f) provided compounds 3a-f and 4a-c. 12H-Chromeno[2,3-d]pyrimidine derivatives 6, 11-13 and 16 were obtained by treatment of 4H-chromene compo

Synthesis and antimicrobial activities of 2-substituted 12H-chromeno[3,2-e][1,2,4] triazolo [1,5-c] pyrimidines, 3-ethoxycarbonyl-12H- chromeno [3,2-e][1,2,4] triazolo [1,5-c] pyrimidine-2-one and ethyl 2-formylamino-and 2-acetylamino-4H-chromene-3-carbox

Preparation of 2-substituted 9-(diethylamino)-12-(4-chlorophenyl)-12H- chromeno[3,2-e][1,2,4]triazolo[1,5-c]pyrimidines is reported. Furthermore, 3-benzylideneamino-5-(4-chlorophenyl)-8-(diethylamino)-4-imino-3, 4-dihydro-5H-chromeno[2,3-d]pyrimidine, 3-e