626253-46-1Relevant academic research and scientific papers
Synthesis of aryl/alkyl(2,2′-bis-3-methylindolyl)methanes and aryl(3,3′-bis indolyl)methanes promoted by secondary amine based ionic liquids and microwave irradiation
Das, Pranab J.,Das, Jupitara
experimental part, p. 4718 - 4720 (2012/09/21)
Aryl/alkyl(2,2′-bis-3-methylindolyl)methanes and aryl(bis-3,3′- indolyl)methanes are synthesized in high yield using ionic liquids mediated by microwave. Reaction conditions and product recovery are simple and ionic liquids could be recycled.
Di- and triindolylmethanes: Molecular structures and spectroscopic characterization of potentially bidentate and tridentate ligands
Mason, Mark R.,Barnard, Thomas S.,Segla, Mawuto F.,Xie, Baohan,Kirschbaum, Kristin
, p. 531 - 540 (2007/10/03)
4-Bromophenyldi(3-methylindol-2-yl)methane (2) and 2-methoxyphenyldi(3- methylindol-2-yl)methane (3) were prepared by sulfuric-acid-catalyzed reactions of 3-methylindole with 4-bromobenzaldehyde and o-anisaldehyde, respectively. Di(3-methylindol-2-yl)phenylmethane (1) and tri(3-methylindol-2-yl)methane (4) were similarly prepared as described previously. Spectroscopic data ( 1H, 13C NMR) and the X-ray crystal structures for 1·C2H5OH and 2-4 are reported. The molecular structure of 1·C2H5OH shows hydrogen bonding of both indolyl NH protons to the oxygen of an ethanol molecule. Crystal data for 1·C2H5OH: Orthorhombic, Pca21, a = 23.9782(17) A, b = 8.4437(7) A, c =11.3029(9) A, V = 2288.4(3) A3, R1 = 0.0597. Crystal data for 2: Orthorhombic, P212121, a = 8.911(3) A, b = 9.584(4) A, c = 24.040(11) A, V = 2053.0(14) A3, R 1 = 0.0454. Crystal data for 3: Monoclinic, P21/c, a = 9.737(2) A, b = 25.035(6) A, c = 9.359(2) A, β= 114.853(4)°, V = 2070.2(8) A3, R1 = 0.0511. Crystal data for 4: Trigonal, R3, a = 14.2214(10) A, c = 9.6190(10) A, V = 1684.8(2) A3, R1 = 0.0425.
