6265-59-4Relevant academic research and scientific papers
Lawesson's reagent and microwaves: A new efficient access to benzoxazoles and benzothiazoles from carboxylic acids under solvent-free conditions
Seijas, Julio A.,Vázquez-Tato, M. Pilar,Carballido-Reboredo, M. Raquel,Crecente-Campo, José,Romar-López, Lucía
, p. 313 - 317 (2007/10/03)
Lawesson's reagent acts as an efficient promoter in the solvent-free microwave-assisted synthesis of 2-substituted benzoxazoles from carboxylic acids and 2-aminophenol, and thus, constitutes a general synthetic method for these compounds. This new application of Lawesson's reagent is valid also for benzothiazoles with very high efficiency level. A variety of aromatic, heteroaromatic and aliphatic carboxylic acids react under the conditions developed with good yields in all cases. Thiobenzoic acid is a good alternative for microwave-assisted synthesis of 2-phenylbenzoxazole and 2- phenylbenzothiazole in the absence of solvents. Georg Thieme Verlag Stuttgart.
An efficient acid- and metal-free one-pot synthesis of benzothiazoles from carboxylic acids
Rudrawar, Santosh,Kondaskar, Atul,Chakraborti, Asit K.
, p. 2521 - 2526 (2007/10/03)
Carboxylic acids are converted to benzothiazoles in a one-pot reaction with thionyl chloride followed by treatment with 2-aminothiophenol under acid- and catalyst-free conditions. Georg Thieme Verlag Stuttgart.
An efficient synthesis of benzothiazoles by direct condensation of carboxylic acids with 2-aminothiophenol under microwave irradiation
Chakraborti, Asit K.,Selvam,Kaur, Gurmeet,Bhagat, Srikant
, p. 851 - 855 (2007/10/03)
Carboxylic acids are converted to benzothiazoles by direct condensation with 2-aminothiophenol under microwave irradiation in the absence of solvent.
