6266-22-4

Usage

Uses

Used in Cosmetics and Personal Care Products:
1-(carboxymethyl)-2-methylpyridinium chloride is used as a preservative for its ability to prevent microbial growth, ensuring the safety and shelf life of cosmetics and personal care products.
Used in Pharmaceuticals:
In the pharmaceutical industry, 1-(carboxymethyl)-2-methylpyridinium chloride is used as a disinfectant to maintain sterility and prevent infections in various medicinal products.
Used in Industrial Applications:
1-(carboxymethyl)-2-methylpyridinium chloride is used as a biocide in industrial settings to control microbial contamination in processes and products, contributing to the safety and quality of the final goods.
Used in Antimicrobial Treatments:
Due to its antimicrobial properties, 1-(carboxymethyl)-2-methylpyridinium chloride is used as an agent in the treatment of infections, potentially serving as an antifungal in certain applications.
1-(carboxymethyl)-2-methylpyridinium chloride is widely approved for use across various consumer and industrial products, highlighting its status as a safe and effective option for controlling microbial growth.

InChI:InChI=1/C8H9NO2.ClH/c1-7-4-2-3-5-9(7)6-8(10)11;/h2-5H,6H2,1H3;1H

Upstream product

• 109-06-8 α-picoline 
• 79-11-8 chloroacetic acid 

Relevant academic research and scientific papers

Valorization of chitin derived N-acetyl-D-glucosamine into high valuable N-containing 3-acetamido-5-acetylfuran using pyridinium-based ionic liquids

Chitin and its derivatives contain biologically fixed nitrogen elements, which can provide nitrogen sources for N-containing chemicals. Herein, a series of pyridinium-based ionic liquids were synthesized to directly catalyze the conversion of N-acetyl-D-glucosamine (NAG, the monomer of chitin) to 3-acetamido-5-acetylfuran (3A5AF). The yield of 3A5AF in 1-carboxymethyl pyridinium chloride ionic liquid reached 37.49%, without any additives. Using B2O3 and CaCl2 as additives, the optimum yield increased to 67.37% at 180 °C in 20 min. In addition, HPLC-MS analysis has been utilized to elucidate the reaction mechanism. This research on turning “waste” into “wealth” opens up new ways for the utilization of biomass waste, which not only reduces environmental pollution but also has potential economic value.

Acidification corrosion inhibitor based on interpolymer indolizine derivative as well as preparation method and application thereof

The invention discloses an acidification corrosion inhibitor based on an interpolymer indolizine derivative as well as a preparation method and application thereof. The acidification corrosion inhibitor contains the interpolymer indolizine derivative; the interpolymer indolizine derivative is prepared by carrying out decarboxylation on heterocyclic alkali including (substituted) quinoline, (substituted) pyridine and the like, and carboxymethyl heterocyclic alkali quaternary ammonium salt obtained by alpha-haloacetic acid, and then carrying out intermolecular addition polymerization reaction onquaternary ammonium salt of the heterocyclic alkali including the (substituted) quinoline, the (substituted) pyridine and the like. The acidification corrosion inhibitor disclosed by the invention has relatively good corrosion inhibition performance under the condition that common corrosion inhibition synergists including alkynol and the like do not need to be compounded; the use amount of the acidification corrosion inhibitor is less and the acidification corrosion inhibitor can reach, even be better than the requirements of an acidification corrosion inhibitor performance testing method andfirst-grade to third-grade standards in evaluation indexes SY/T 5405-1996 when being independently used.

Benzimidazolone as potent chymase inhibitor: Modulation of reactive metabolite formation in the hydrophobic (P1) region

A new class of chymase inhibitor featuring a benzimidazolone core with an acid side chain and a P1 hydrophobic moiety is described. Incubation of the lead compound with GSH resulted in the formation of a GSH conjugate on the benzothiophene P1 moiety. Replacement of the benzothiophene with different heterocyclic systems such as indoles and benzoisothiazole is feasible. Among the P1 replacements, benzoisothiazole prevents the formation of GSH conjugate and an in silico analysis of oxidative potentials agreed with the experimental outcome.

Synthesis and antioxidant activity of 3,3′-diselanediylbis (N,N-disubstituted indolizine-1-carboxamide) and derivatives

A series of novel diselenides 5a-e were synthesized from α-haloketones, α-picoline alkenes and various secondary amines under a dry nitrogen atmosphere. The structures of these compounds were established by means of their spectral data and they were screened for scavenging activity against 1,1-diphenyl-2-picryl-hydrazyl (DPPH.). The results of this research showed that two of these compounds (5e and 5d) exhibited reasonable antioxidant activity. The intermediate, methyl 5-methylindolizine-1-carboxylate was prepared by condensation of methyl acrylate with 1-(carboxymethyl)-2- methylpyridinium halide, which was prepared from α-picoline and chloroacetic acid by using the Tschischibabin reaction.

BENZIMIDAZOLONE CHYMASE INHIBITORS

Disclosed are small molecule inhibitors which are useful in treating various diseases and conditions involving chymase.

A novel and practical synthesis of 3-unsubstituted indolizines

A novel and practical procedure for the preparation of 3-unsubstituted indolizines by 1,3-dipolar cycloaddition was developed. The requisite pyridinium N-methylides were generated simply from the corresponding N-(carboxymethyl)pyridinium halides. In the presence of MnO2, electron-deficient alkenes, instead of alkynes or vinyl bromides, were used successfully as dipolarophiles. This general method features cheap reagents, simple workup procedure and gives the products in moderate to high yields (57-92%).