6267-14-7

Usage

Uses

Used in Pharmaceutical Research:
(thiophen-3-ylsulfanyl)acetic acid is used as a building block for the development of drugs targeting neurological and psychiatric disorders. Its unique structure allows for the creation of novel molecules with potential therapeutic effects on various conditions.
Used in Organic Synthesis:
In the field of organic synthesis, (thiophen-3-ylsulfanyl)acetic acid is utilized as a key component in the synthesis of complex molecules. Its thiophenyl group and sulfur linkage provide a foundation for constructing a diverse range of chemical compounds.
Used in Antimicrobial Applications:
(thiophen-3-ylsulfanyl)acetic acid is employed as an antimicrobial agent, demonstrating potential in combating bacterial infections. Its properties make it a candidate for further research and development in the creation of new antimicrobial drugs.
Used in Antifungal Applications:
Similarly, (thiophen-3-ylsulfanyl)acetic acid has been investigated for its antifungal properties, showing promise in the development of treatments for fungal infections. Its structure and properties contribute to its potential as a valuable tool in the fight against various fungal pathogens.

Upstream product

• 7774-73-4 thiophene-3-thiol 
• 79-11-8 chloroacetic acid 
• 872-31-1 3-Bromothiophene 
• 73318-56-6 bromoacetic acid,potassium salt 

Downstream Products

• 37882-75-0 2,5-Thieno<3,2-b>thiophendicarbaldehyd 

Relevant academic research and scientific papers

Linearly extended tetrathiafulvalene analogues with fused thiophene units as π-conjugated spacers

A new series of linearly extended tetrathiafulvalene analogues with thienothiophene and dithienothiophene π-conjugating spacers has been synthesized. Electronic absorption spectra present a vibronic fine structure typical for rigid conjugated systems. Investigation of the electrochemical behaviour of the new donors by cyclic voltammetry reveals the successive generation of stable radical cation and dication species. The crystallographic structure of a single crystal of a dication salt of TT-TTF(ClO4)2 has been analysed by X-ray diffraction. The dication presents a syn conformation stabilised by S...S intramolecular interactions. The quinoid structure expected for the spacer for the +2 oxidation state is clearly revealed by the bond lengths.

Electrophilic Aromatic Substitution. Part 31. Partial Rate Factors for Detritiation of Thienothiophen and Thienothiophen: Weak Hydrogen Bonding to Sulphur in Trifluoroacetic Acid

Thienothiophen (I) and thienothiophen (II), specifically labelled with tritium in each position have been prepared, and their rates of protiodetritiation measured along with that for thiophen in either pure trifluoroacetic acid, or mixtures of trifluoroacetic acid and acetic acid, all at 70 deg C.The dependence of exchange rate coefficients upon acid composition indicates that the ring sulphur is hydrogen bonded, and to an extent which depends upon the number of sulphur atoms in the heterocycle.Partial rate factors for detritiation of the non-hydrogen-bonded compounds are calculated as follows (position and compound in parentheses): 7.18E8 ; 6.83E8 ; 9.75E7 (2-thiophen); 7.59E5 ; 5.54E5 ; 7.84E4 (3-thiophen), the corresponding ?+-values being -1.012, -1.010, -0.913, -0.672, -0.656, and -0.560.The results, taken along with those for acylation and chlorination show that (II) is more polarisable than (I), so that these compounds, like all other ?-excessive heterocycles previously examined, are unsuitable for rigorous application of the Extended Selectivity Relationship.Annelation of thiophen by thiophen produces a comparable change in reactivities of the α- and β-positions in contrast to annelation by benzene, where the high resonance energy of benzene plays a crucial role in raising the reactivity of the β-position, relative to that of the α-position.